{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T13:10:34Z","timestamp":1774444234099,"version":"3.50.1"},"reference-count":54,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2004,10,9]],"date-time":"2004-10-09T00:00:00Z","timestamp":1097280000000},"content-version":"vor","delay-in-days":10190,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Comparative Neurology"],"published-print":{"date-parts":[[1976,11,15]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Three aspects of the labelling pattern seen after the injection of 13 different radioactive amino acids into the pigeon optic tectum have been described: The efferent projections of the optic tectum; the specific labelling of two pathways; and the dendritic organisation of tectal layer III neurons based on the retrograde and anterograde movement of label within these dendrites.<\/jats:p><jats:p>Discrete injections of tritiated amino acid that involved all or only the superficial tectal layers suggested that layer III gave rise to the massive non\u2010topographically organised and bilateral projections (fibers crossing within the decussatio supraoptica ventralis) upon the nuclei rotundus, subpraetectalis and interstitio\u2010praetecto\u2010subpraetectalis and to the ipsilaterally directed pathways terminating within the nuclei praetectalis, triangularis, subrotundus, dorsolateralis anterior thalami, posteroventralis and ventrolateralis thalami. Layer III neurons may also be the source of efferents to the posterior dorsolateral thalamus (the layer III pathway), the pontine grey and, bilaterally to the reticular formation and of the layer IV or tectal commissural pathway terminating within the contralateral tectal cortex. In contrast projections originating from layer II were generally topographically organised and terminated either within certain of the isthmic nuclei (n. isthmi pars parvocellularis, n. isthmo\u2010opticus and n. semilunaris) or ran within layer I (layer I pathway) to end in the pretectum (griseum tectale) and ventral thalamus (n. ventrolateralis thalami, n. geniculatus, pars ventralis). A small projection from layer II upon the ipsilateral nucleus rotundus may also be present.<\/jats:p><jats:p>Tritiated serine and tyrosine were found to be particularly effective in labelling perikarya as well as axons and terminals. The layer I pathway could be selectively labelled after tectal injections of <jats:sup>3<\/jats:sup>H\u2010GABA while the cell bodies of Ipc neurons were labelled in a retrograde fashion after tectal injections of <jats:sup>3<\/jats:sup>H\u2010glycine, serine or alanine.<\/jats:p><jats:p>Intrinsic tectal labelling was found by correlation with Golgi material to reflect both anterograde and retrograde transport of label within dendrites of layer III cells. Anterograde movement of label indicated that the terminal portions of layer III cell dendrites ended in an orderly radial arrangement within sublayers IIb and IId, while the retrograde movement of label resulted in the labelling of layer III perikarya outside the injection field.<\/jats:p>","DOI":"10.1002\/cne.901700203","type":"journal-article","created":{"date-parts":[[2005,5,27]],"date-time":"2005-05-27T21:00:52Z","timestamp":1117227652000},"page":"153-172","source":"Crossref","is-referenced-by-count":237,"title":["Observations on the projections and intrinsic organization of the pigeon optic tectum: An autoradiographic study based on anterograde and retrograde, axonal and dendritic flow"],"prefix":"10.1002","volume":"170","author":[{"given":"S. P.","family":"Hunt","sequence":"first","affiliation":[]},{"given":"H.","family":"K\u00fcnzle","sequence":"additional","affiliation":[]}],"member":"311","published-online":{"date-parts":[[2004,10,9]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901160206"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(74)91039-7"},{"key":"e_1_2_1_4_1","unstructured":"Benowitz L. I. andH. J.Karten1975Organisation of the tectofugal visual pathway in pigeon. Abstr. presented at 5th Annual Meeting of the Society for Neuroscience New York p.46."},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901670407"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.900920104"},{"key":"e_1_2_1_7_1","first-page":"141","article-title":"Centros \u00f3pticos de las aves","volume":"3","author":"Cajal P. R.","year":"1898","journal-title":"Revtr. trimest. microgr."},{"key":"e_1_2_1_8_1","first-page":"77","article-title":"Adiciones a nuestros trabajos sobre los centros \u00f3pticos de las aves","volume":"4","author":"Cajal P. R.","year":"1899","journal-title":"Revtr. trimest. microgr."},{"key":"e_1_2_1_9_1","first-page":"337","article-title":"Sur la fine structure du lobe optique des oiseaux et sur l'origine r\u00e9elle des nerfs optiques","volume":"8","author":"Cajal S. R.","year":"1891","journal-title":"Int. Mschr. Anat. Physiol."},{"key":"e_1_2_1_10_1","volume-title":"Histologie du syst\u00e9me nerveux","author":"Cajal S. R.","year":"1911"},{"key":"e_1_2_1_10_2","volume-title":"Histologie du syst\u00e9me nerveux","year":"1955"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1974.sp010753"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.bmb.a070760"},{"key":"e_1_2_1_13_1","first-page":"545","article-title":"An experimental study of the avian visual system","volume":"95","author":"Cowan W. M.","year":"1961","journal-title":"J. Anat. (London)"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(72)90344-7"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(72)90667-1"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(67)90166-7"},{"key":"e_1_2_1_17_1","first-page":"1","article-title":"La structure des lobes optiques chez l'embryon du poulet","volume":"8","author":"van Gehuchten A.","year":"1892","journal-title":"Cellule"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(75)90566-1"},{"key":"e_1_2_1_19_1","unstructured":"Hart J. R.1969Some Observations on the Development of the Avian Optic Tectum. Unpublished thesis. University of Wisconsin."},{"key":"e_1_2_1_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901480305"},{"key":"e_1_2_1_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901620404"},{"key":"e_1_2_1_22_1","doi-asserted-by":"publisher","DOI":"10.1159\/000125822"},{"key":"e_1_2_1_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00240403"},{"key":"e_1_2_1_24_1","doi-asserted-by":"publisher","DOI":"10.1159\/000123663"},{"key":"e_1_2_1_25_1","first-page":"249","volume-title":"The Use of Axonal Transport for Studies of Neuronal Connectivity","author":"H\u00f6kfelt T.","year":"1975"},{"key":"e_1_2_1_26_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1972.sp009856"},{"key":"e_1_2_1_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(74)91023-3"},{"key":"e_1_2_1_28_1","unstructured":"Hunt S. P. 1973A Study of Forebrain Visual Areas in the Pigeon. Unpublished thesis. University of London."},{"key":"e_1_2_1_29_1","doi-asserted-by":"crossref","unstructured":"Hunt S. P. andH.Henke H.K\u00fcnzle.J. C.Reubi T.Schenker P.Streit D.FelixandM.Cu\u00e9nod1976aBiochemical neuroanatomy of the pigeon optic tectum. Exp. Brain Res. in press.","DOI":"10.1007\/978-3-642-81055-8_98"},{"key":"e_1_2_1_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901700204"},{"key":"e_1_2_1_31_1","first-page":"97","article-title":"The retrograde transport of amino acids and a glycinergic system within the pigeon optic lobe","volume":"23","author":"Hunt S. P.","year":"1975","journal-title":"Exp. Brain Res."},{"key":"e_1_2_1_32_1","unstructured":"Hunt S. P. P.Streit H.K\u00fcnzleandM.Cu\u00e9nod(1976b in preparation)Selective uptake and retrograde movement of label within the pigeon isthmo\u2010tectal pathway after injection of radioactive glycine serine alanine choline and GABA."},{"key":"e_1_2_1_33_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901620403"},{"key":"e_1_2_1_34_1","first-page":"23","article-title":"Ascending pathways from the spinal cord in the pigeon (Columba livia)","volume":"2","author":"Karten H. J.","year":"1963","journal-title":"Proc. XVI Internat. Cong. Zool."},{"key":"e_1_2_1_35_1","first-page":"369","article-title":"Projections of the optic tectum of the pigeon (Columba livia)","volume":"151","author":"Karten H. J.","year":"1965","journal-title":"Anat. Rec."},{"key":"e_1_2_1_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(67)90055-8"},{"key":"e_1_2_1_37_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1969.tb20442.x"},{"key":"e_1_2_1_38_1","volume-title":"A Stereotaxic Atlas of the Brain of the Pigeon (Columba livia)","author":"Karten H. J.","year":"1967"},{"key":"e_1_2_1_39_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901500303"},{"key":"e_1_2_1_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(66)90006-0"},{"key":"e_1_2_1_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(73)90016-4"},{"key":"e_1_2_1_42_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901470404"},{"key":"e_1_2_1_43_1","first-page":"5","article-title":"The retinal representation upon the optic tectum and isthmo\u2010optic nucleus in the pigeon","volume":"100","author":"McGill J. I.","year":"1966","journal-title":"J. Anat. (London)"},{"key":"e_1_2_1_44_1","first-page":"35","article-title":"The organization of the projection of the centrifugal fibres to the retina in the pigeon","volume":"100","author":"McGill J. I.","year":"1966","journal-title":"J. Anat. (London)"},{"key":"e_1_2_1_45_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00424607"},{"key":"e_1_2_1_46_1","doi-asserted-by":"publisher","DOI":"10.1159\/000228812"},{"key":"e_1_2_1_47_1","first-page":"151","article-title":"Nouvelles donn\u00e9es sur les projections visuelles chez le pigeon (Columba livia)","volume":"14","author":"Rep\u00e9rant J.","year":"1973","journal-title":"J. Hirnforsch."},{"key":"e_1_2_1_48_1","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1159\/000125471","article-title":"Some characteristics of wide\u2010field units in the brain of the pigeon","volume":"3","author":"Revzin A. M.","year":"1970","journal-title":"Brain, Behav. and Evol."},{"key":"e_1_2_1_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(67)90077-7"},{"key":"e_1_2_1_50_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00238325"},{"key":"e_1_2_1_51_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00238326"},{"key":"e_1_2_1_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(72)90806-2"},{"key":"e_1_2_1_53_1","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1159\/000123627","article-title":"Interhemispheric projections of the optic tectum in pigeon","volume":"11","author":"Voneida T. J.","year":"1975","journal-title":"Brain, Behav. and Evol."},{"key":"e_1_2_1_54_1","first-page":"258","volume-title":"Essays on the Nervous System","author":"Webster K. E.","year":"1974"}],"container-title":["Journal of Comparative Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fcne.901700203","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cne.901700203","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,13]],"date-time":"2023-11-13T03:40:20Z","timestamp":1699846820000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/cne.901700203"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1976,11,15]]},"references-count":54,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1976,11,15]]}},"alternative-id":["10.1002\/cne.901700203"],"URL":"https:\/\/doi.org\/10.1002\/cne.901700203","archive":["Portico"],"relation":{},"ISSN":["0021-9967","1096-9861"],"issn-type":[{"value":"0021-9967","type":"print"},{"value":"1096-9861","type":"electronic"}],"subject":[],"published":{"date-parts":[[1976,11,15]]}}}