{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,10]],"date-time":"2026-01-10T08:09:43Z","timestamp":1768032583289,"version":"3.49.0"},"reference-count":85,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2004,10,9]],"date-time":"2004-10-09T00:00:00Z","timestamp":1097280000000},"content-version":"vor","delay-in-days":8866,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Comparative Neurology"],"published-print":{"date-parts":[[1980,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The boundaries of the second somatic sensory cortex (SII) in primates are difficult to define physiologically because cutaneous stimulation activates several regions around SII that do not receive projections from the ventroposterior nucleus of the thalamus. These cortical regions, which include portions of area 7b, the retroinsular (Ri) and postauditory fields (PA), and the granular insula (Ig) are largely buried within the lateral sulcus and most lie posterior to the caudal end of the insula. The differences in somatic activity in these various cortical fields in the unanesthetized cynomolgus monkey became apparent only after the properties of many neighboring neurons could be compared. Receptive fields for area 7b and Ig neurons were generally large (&gt; 10cm<jats:sup>2<\/jats:sup>), with bilateral, moderately defined boundaries; some neurons in area 7b had receptive fields with labile borders as a function of wakefulness. In contrast, receptive fields for Ri neurons were generally &lt; 10cm<jats:sup>2<\/jats:sup> and contralateral, with stable, well\u2010defined boundaries.<\/jats:p><jats:p>Taken as an ensemble, the neurons in areas neighboring SII exhibited a very crude topography; but at the level of an individual neuron and its neighbor, there was never a pattern of gradual transition in peripheral receptive field locations between one unit and the next, like that seen in SII. In area 7b, this crude map was organized mediolaterally across the inferior parietal lobule and into the upper bank of the lateral sulcus, with the head represented medially and the lower trunk and hindlimb laterally. In Ri\u2010PA, an anteroposterior organization was noted along the fundus of the lateral sulcus with the head represented anterior to the lower trunk and hindlimb. No organization was apparent in Ig. Additional sensitivity to visual stimuli was noted in the more medial aspects of area 7b that were located on the exposed inferior parietal lobule. Sensitivity to auditory stimuli was principally found in PA and occasionally in Ri. The results, especially from area 7b, are discussed with respect to previous notions about the organization of SII.<\/jats:p>","DOI":"10.1002\/cne.901920105","type":"journal-article","created":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T23:16:33Z","timestamp":1104621393000},"page":"69-92","source":"Crossref","is-referenced-by-count":271,"title":["Organization of somatosensory receptive fields in cortical areas 7b, retroinsula, postauditory and granular insula of <i>M. fascicularis<\/i>"],"prefix":"10.1002","volume":"192","author":[{"given":"C. J.","family":"Robinson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Burton","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,10,9]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/0304-3940(77)90128-8","article-title":"Topographic distribution of visual and somesthetic unitary responses in the Pul\u2010LP complex of the cat","volume":"4","author":"Avanzini G.","year":"1977","journal-title":"Neurosci. Lett."},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00239039"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901600306"},{"key":"e_1_2_1_5_1","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1152\/jn.1957.20.3.286","article-title":"Somatic receiving areas of cerebral cortex of squirrel monkey (Saimiri sciureus)","volume":"20","author":"Benjamin R. M.","year":"1957","journal-title":"J. Neurophysiol."},{"key":"e_1_2_1_6_1","doi-asserted-by":"crossref","first-page":"940","DOI":"10.1152\/jn.1973.36.5.940","article-title":"Response properties of cells in ventrobasal and posterior group nuclei of the cat","volume":"36","author":"Berkley K. J.","year":"1973","journal-title":"J. Neurophysiol."},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901800205"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901740204"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(70)90379-3"},{"key":"e_1_2_1_10_1","first-page":"331","article-title":"The termination of the spinothalamic tract in the cat. An experimental study with silver impregnation methods","volume":"19","author":"Boivie J.","year":"1971","journal-title":"Exp. Brain Res."},{"key":"e_1_2_1_11_1","first-page":"274","article-title":"Anatomical features of somatosensory projections to the ventral, posterior and intralaminar regions in primates","volume":"57","author":"Boivie J.","year":"1978","journal-title":"Acta Neurol. Scand."},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901860304"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901830406"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901680204"},{"key":"e_1_2_1_15_1","first-page":"102","article-title":"Physiological and anatomical studies of neurons within the sylvian fissure of cynomolgus monkeys which respond to innocuous and\/or noxious stumuli","volume":"1","author":"Burton H.","year":"1978","journal-title":"Second World Congress on Pain. Pain Abstr."},{"key":"e_1_2_1_16_1","first-page":"548","article-title":"A single unit study of cortical areas adjacent to the second somatic sensory cortex in the cynomolgus monkey","volume":"4","author":"Burton H.","year":"1978","journal-title":"Neurosci. Abstr."},{"key":"e_1_2_1_17_1","volume-title":"Multiple Cortical Sensory Areas","author":"Burton H.","year":"1980"},{"key":"e_1_2_1_18_1","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1016\/0006-8993(78)90421-3","article-title":"Parietal cortex (2v) neuronal activity in the alert monkey during natural vestibular and optokinetic stimulation","volume":"152","author":"B\u00fcttner U.","year":"1978","journal-title":"Brain Res."},{"key":"e_1_2_1_19_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1965.sp007707"},{"key":"e_1_2_1_20_1","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1152\/jn.1963.26.1.100","article-title":"Functional properties of neurons of the anterior ectosylvian gyrus of the cat","volume":"26","author":"Carreras M.","year":"1963","journal-title":"J. Neurophysiol."},{"key":"e_1_2_1_21_1","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1152\/jn.1966.29.4.727","article-title":"Unit analysis of nociceptive mechanisms in the thalamus of the awake squirrel monkey","volume":"29","author":"Casey K. L.","year":"1966","journal-title":"J. Neurophysiol."},{"key":"e_1_2_1_22_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1977.sp011971"},{"key":"e_1_2_1_23_1","volume-title":"The Parietal Lobes","author":"Critchley J.","year":"1953"},{"key":"e_1_2_1_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(72)90313-7"},{"key":"e_1_2_1_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(72)90312-5"},{"key":"e_1_2_1_26_1","doi-asserted-by":"publisher","DOI":"10.1001\/archneurpsyc.1954.02320390032003"},{"key":"e_1_2_1_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(77)90474-7"},{"key":"e_1_2_1_28_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.1975.38.3.690"},{"key":"e_1_2_1_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(78)90632-7"},{"key":"e_1_2_1_30_1","doi-asserted-by":"crossref","unstructured":"Friedman D. P. Jones E. G. andBurton H.(1980) Representation pattern in the second somatic sensory area of the monkey cerebral cortex.J. Comp. Neurol.(this issue).","DOI":"10.1002\/cne.901920103"},{"key":"e_1_2_1_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(78)90007-0"},{"key":"e_1_2_1_32_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901730403"},{"key":"e_1_2_1_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(70)90409-9"},{"key":"e_1_2_1_34_1","doi-asserted-by":"publisher","DOI":"10.1159\/000123723"},{"key":"e_1_2_1_35_1","first-page":"38","article-title":"Single units activities in ventral posterior and posterior group thalamic nuclei during nociceptive and non\u2010nociceptive stimulations in the cat","volume":"115","author":"Guilbaud G.","year":"1977","journal-title":"Arch. Ital. Biol."},{"key":"e_1_2_1_36_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901410402"},{"key":"e_1_2_1_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(79)90404-9"},{"key":"e_1_2_1_38_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901540404"},{"key":"e_1_2_1_39_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901680203"},{"key":"e_1_2_1_40_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901880110"},{"key":"e_1_2_1_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(73)90115-7"},{"key":"e_1_2_1_42_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/93.4.793"},{"key":"e_1_2_1_43_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901830410"},{"key":"e_1_2_1_44_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901770409"},{"key":"e_1_2_1_45_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901590304"},{"key":"e_1_2_1_46_1","first-page":"148","volume-title":"Advances in Neurology","author":"Kerr F. W. L.","year":"1974"},{"key":"e_1_2_1_47_1","first-page":"8","article-title":"Intraural interaction in monkey auditory cortex","volume":"4","author":"Legatt A. D.","year":"1978","journal-title":"Neurosci. Abstr."},{"key":"e_1_2_1_48_1","first-page":"299","article-title":"I. Functional properties of neurons in lateral part of associative area 7 in awake monkeys","volume":"34","author":"Leinonen L.","year":"1979","journal-title":"Exp. Brain Res."},{"key":"e_1_2_1_49_1","first-page":"321","article-title":"II. Functional properties of cells in anterolateral part of area 7 associative face area of awake monkeys","volume":"34","author":"Leinonen L.","year":"1979","journal-title":"Exp. Brain Res."},{"key":"e_1_2_1_50_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.1976.39.3.601"},{"key":"e_1_2_1_51_1","first-page":"555","article-title":"Thalamic projections to S\u2013II cortex of rhesus monkey","volume":"4","author":"Loe P. R.","year":"1978","journal-title":"Neurosci. Abstr."},{"key":"e_1_2_1_52_1","first-page":"486","article-title":"Projections from the spinal cord and the gracile, cuneate, trigeminal and lateral cervical nuclei to the posterior group of nuclei in the thalamus of the cat","volume":"3","author":"Mash D. C.","year":"1977","journal-title":"Neurosci. Abstr."},{"key":"e_1_2_1_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(73)90171-6"},{"key":"e_1_2_1_54_1","first-page":"11","volume-title":"Pain","author":"Mehler W. R.","year":"1966"},{"key":"e_1_2_1_55_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/83.4.718"},{"key":"e_1_2_1_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(73)90731-2"},{"key":"e_1_2_1_57_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.1975.38.4.871"},{"key":"e_1_2_1_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4886(74)90083-1"},{"key":"e_1_2_1_59_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00523634"},{"key":"e_1_2_1_60_1","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4886(61)90016-4"},{"key":"e_1_2_1_61_1","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1152\/jn.1979.42.1.123","article-title":"Acoustic input to single neurons in pulvinar\u2010posterior complex of cat thalamus","volume":"42","author":"Phillips D. P.","year":"1979","journal-title":"J. Neurophysiol."},{"key":"e_1_2_1_62_1","first-page":"266","article-title":"A study of the functional contributions of the lemniscal and spinothalamic systems to somatic sensibility","volume":"106","author":"Poggio G. F.","year":"1960","journal-title":"Bull. Johns Hopkins Hosp."},{"key":"e_1_2_1_63_1","first-page":"490","article-title":"Responses to somatic stimulation in N. parafascicularis (Pf) and in the posterior group of nuclei (PO) in the unanesthetized cat","volume":"3","author":"Pugh W. W.","year":"1977","journal-title":"Neurosci. Abstr."},{"key":"e_1_2_1_64_1","first-page":"1","article-title":"Insular and opercular cortex and its thalamic projection in Macaca mulatta","volume":"9","author":"Roberts T. S.","year":"1963","journal-title":"Schweiz. Arch. Neurol. Neurochir. Psychiatr."},{"key":"e_1_2_1_65_1","first-page":"557","article-title":"A single unit study of the second somatic sensory cortex in the cynomologous monkey","volume":"4","author":"Robinson C. J.","year":"1978","journal-title":"Neurosci. Abstr."},{"key":"e_1_2_1_66_1","doi-asserted-by":"crossref","unstructured":"Robinson C. J. andH.Burton(1980a) Somatotopographic organization in the second somatosensory area ofM. fascicularis.J. Comp. Neurol.(this issue).","DOI":"10.1002\/cne.901920104"},{"key":"e_1_2_1_67_1","doi-asserted-by":"crossref","unstructured":"Robinson C. J. andH.Burton(1980b) Somatic submodality distribution within the second somatosensory (SII) 7b retroinsular postauditory and granular insular cortical areas.J. Comp. Neurol.(this issue).","DOI":"10.1002\/cne.901920106"},{"key":"e_1_2_1_68_1","first-page":"2258","article-title":"Sensory and behavioral properties of neurons in posterior parietal cortex of the awake, trained monkey","volume":"37","author":"Robinson D. L.","year":"1978","journal-title":"Fed. Proc."},{"key":"e_1_2_1_69_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.1978.41.4.910"},{"key":"e_1_2_1_70_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(79)90388-3"},{"key":"e_1_2_1_71_1","first-page":"469","article-title":"Die inselrinde des menschen und tier","volume":"37","author":"Rose M.","year":"1928","journal-title":"J. Psychol. Neurol. (Leipzig)"},{"key":"e_1_2_1_72_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(73)90172-8"},{"key":"e_1_2_1_73_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.172.3980.280"},{"key":"e_1_2_1_74_1","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3940(77)90025-8"},{"key":"e_1_2_1_75_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(78)90006-9"},{"key":"e_1_2_1_76_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901830205"},{"key":"e_1_2_1_77_1","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1152\/jn.1976.39.2.401","article-title":"Relationships between visual and tactile representations in cat superior colliculus","volume":"39","author":"Stein B. E.","year":"1976","journal-title":"J. Neurophysiol."},{"key":"e_1_2_1_78_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.1978.41.2.268"},{"key":"e_1_2_1_79_1","first-page":"277","article-title":"Allgemeinere ergebnisse unserer hirnforschung","volume":"25","author":"Vogt C.","year":"1919","journal-title":"J. Psychol. Neurol. (Leipzig)"},{"key":"e_1_2_1_80_1","volume-title":"Illinois Monographs in the Medical Sciences","author":"Von Bonin G.","year":"1947"},{"key":"e_1_2_1_81_1","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1152\/jn.1969.32.2.170","article-title":"Symmetry and connectivity in the map of the body surface in somatosensory area II of primates","volume":"32","author":"Whitsel B. L.","year":"1969","journal-title":"J. Neurophysiol."},{"key":"e_1_2_1_82_1","first-page":"53","article-title":"Additional observations on a \u201csecond\u201d somatic receiving area in the cerebral cortex of the monkey","volume":"3","author":"Woolsey C. N.","year":"1944","journal-title":"Fed. Proc."},{"key":"e_1_2_1_83_1","first-page":"63","volume-title":"Biological and Biochemical Basis of Behavior","author":"Woolsey C. N.","year":"1958"},{"key":"e_1_2_1_84_1","first-page":"684","article-title":"Contralateral, ipsilateral and bilateral representation of cutaneous receptors in somatic areas I and II of the cerebral cortex of pig, sheep and other mammals","volume":"19","author":"Woolsey C. N.","year":"1946","journal-title":"Surgery"},{"key":"e_1_2_1_85_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3956(78)90028-6"},{"key":"e_1_2_1_86_1","first-page":"2251","article-title":"Mechanisms of neural integration in the parietal lobe for visual attention","volume":"37","author":"Yin T. C. T.","year":"1978","journal-title":"Fed. Proc."}],"container-title":["Journal of Comparative Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fcne.901920105","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cne.901920105","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,13]],"date-time":"2023-11-13T03:21:01Z","timestamp":1699845661000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/cne.901920105"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1980,7]]},"references-count":85,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1980,7]]}},"alternative-id":["10.1002\/cne.901920105"],"URL":"https:\/\/doi.org\/10.1002\/cne.901920105","archive":["Portico"],"relation":{},"ISSN":["0021-9967","1096-9861"],"issn-type":[{"value":"0021-9967","type":"print"},{"value":"1096-9861","type":"electronic"}],"subject":[],"published":{"date-parts":[[1980,7]]}}}