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Immunoblots of cat visual cortex tissue with these antibodies revealted that antibody \u201cQ\u201d recognizes only one subunit, namely the \u03b2<jats:sub>1<\/jats:sub>\u2010subunit of the GABA<jats:sub>A<\/jats:sub> receptor, and that antibody \u201c967\u201d recognizes three subunits. Both antibodies produced very similar staining patterns, indicating that the \u03b2<jats:sub>1<\/jats:sub>\u2010subunit may be an essential component of the GABA<jats:sub>A<\/jats:sub> receptor in the cat visual cortex. The typical staining pattern showed a clear membrane structure around neuronal somata. Using cell body shape criteria, immunopositive neurons included both pyramidal cells in cortical layers II, III, and V, and nonpyramidal cells in all cortical layers. Immunopositive neurons were uniformly distributed in layers II to VI, whereas the density of immunopositive cells in layer I was lower. Some immunopositive neurons were also found in the white matter underlying the visual cotex. In gray matter, immunopositive structures also included dendrites, especially the proximal dendrites, and axon initial segments of pyramidal neurons. The immunopositive processes usually ran vertically toward the pial surface. Some astrocytes were also immunostained. They were localized in layer I and in the white matter. 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