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First, at limiting dilutions, mixtures of plaqueforming cells (PFC) of different specificities occur significantly more often than is expected from chance overlap of 2 clones. Second, PFC releasing uncommon, highly cross\u2010reactive antibody grow into clones which are much smaller than average, in mitogen\u2010stimulated cultures. This suggests that PFC of such rare types arise within clones initially producing other antibody specificities.<\/jats:p>","DOI":"10.1002\/eji.1830041111","type":"journal-article","created":{"date-parts":[[2007,2,27]],"date-time":"2007-02-27T23:39:21Z","timestamp":1172619561000},"page":"762-767","source":"Crossref","is-referenced-by-count":28,"title":["The generation of antibody diversity. III. 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