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One of the lines possessed virus\u2010like particles of the Epstein\u2010Barr type. All the established lines were capable of mediating antibody\u2010dependent cytotoxicity (LADC) quantitatively at a level not significantly different from that mediated by freshly isolated, normal human peripheral blood lymphocytes (PBL). The LADC of the lymphoblasts was inhibited by all the human IgG subclasses tested (IgG1, IgG2, IgG3, IgG4) as was the LADC of PBL. It is concluded that, at least so far, the lymphoblasts have retained the properties of the lymphocytes from which they were originally derived as regards their ability to mediate LADC.<\/jats:p>","DOI":"10.1002\/eji.1830050410","type":"journal-article","created":{"date-parts":[[2007,2,28]],"date-time":"2007-02-28T01:45:39Z","timestamp":1172627139000},"page":"266-270","source":"Crossref","is-referenced-by-count":4,"title":["Human lymphoblast cell lines: Antibody\u2010dependent cytotoxicity"],"prefix":"10.1002","volume":"5","author":[{"given":"J.\u2010C.","family":"Lefebre","sequence":"first","affiliation":[]},{"given":"A.","family":"Petitprez","sequence":"additional","affiliation":[]},{"given":"D.","family":"Juy","sequence":"additional","affiliation":[]},{"given":"C.","family":"Bona","sequence":"additional","affiliation":[]}],"member":"311","published-online":{"date-parts":[[2005,12,7]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"471","volume-title":"Membrane Molecular Biology","author":"Herschman H. 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