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The \u03b2 chain of the T cell receptor is composed of V<jats:sub>\u03b2<\/jats:sub>8.1, D<jats:sub>\u03b2<\/jats:sub> and J<jats:sub>\u03b2<\/jats:sub>2.4 gene segments while the \u03b1 chain uses a member of the V<jats:sup>\u03b1<\/jats:sup>2 family and J<jats:sup>\u03b1<\/jats:sup> TA31. Southern blot analysis of a panel of six other independent LCMV\u2010specific cytotoxic T cell clones did not reveal any preferential usage of the V<jats:sub>\u03b1<\/jats:sub>2 or V\u03b28 gene families in the cytotoxic LCMV response. Additionally, we have isolated and sequenced cDNA clones derived from the non\u2010functionally rearranged \u03b1 allele of P14. This transcript is composed of a unique V<jats:sub>\u03b1<\/jats:sub> gene segment which belongs to a new V<jats:sub>\u03b1<\/jats:sub> gene family.<\/jats:p>","DOI":"10.1002\/eji.1830171226","type":"journal-article","created":{"date-parts":[[2007,3,1]],"date-time":"2007-03-01T00:00:15Z","timestamp":1172707215000},"page":"1843-1846","source":"Crossref","is-referenced-by-count":78,"title":["Molecular analysis of the antigen receptor of virus\u2010specific cytotoxic T cells and identification of a new V<sub>\u03b1<\/sub> family"],"prefix":"10.1002","volume":"17","author":[{"given":"Hanspeter","family":"Pircher","sequence":"first","affiliation":[]},{"given":"E. 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