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The level of <jats:italic>bcl\u20102<\/jats:italic> mRNA was identical in the wild type and the variants, either untreated or anti\u2010Ig treated, suggesting that PCD is not under the control of <jats:italic>bcl\u20102<\/jats:italic> in WEHI\u2010231 cells. In contrast, <jats:italic>c\u2010myc<\/jats:italic> gene expression was markedly different in the wild type and the variants, both in the unstimulated and anti\u2010Ig\u2010stimulated state. Our findings are interpreted in the context of the dual capacity of <jats:italic>c\u2010myc<\/jats:italic> to promote cell growth or cell death, in conjunction with other growth regulatory signals.<\/jats:p>","DOI":"10.1002\/eji.1830231115","type":"journal-article","created":{"date-parts":[[2007,3,1]],"date-time":"2007-03-01T18:30:29Z","timestamp":1172773829000},"page":"2821-2825","source":"Crossref","is-referenced-by-count":26,"title":["Signaling of programmed cell death induction in WEHI\u2010231 B lymphoma cells"],"prefix":"10.1002","volume":"23","author":[{"given":"Urszula","family":"Hibner","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laure E.","family":"Benhamou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthias","family":"Haury","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pierre\u2010Andr\u00e9","family":"Cazenave","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pierre","family":"Sarthou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,12,8]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-065X.1987.tb00504.x"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-065X.1987.tb01176.x"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/eji.1830200630"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/eji.1830200810"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1038\/335440a0"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(89)90174-8"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.88.19.8661"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(91)90361-2"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(91)90362-3"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(92)90123-T"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1038\/359552a0"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1038\/359554a0"},{"key":"e_1_2_1_14_2","first-page":"1257","volume":"8","author":"Haury M.","year":"1993","journal-title":"Oncogene"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/eji.1830210819"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.bi.61.070192.004113"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.81.17.5546"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1002\/eji.1830190715"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/12.18.7035"},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(87)90448-X"},{"key":"e_1_2_1_21_2","doi-asserted-by":"publisher","DOI":"10.1038\/348331a0"},{"key":"e_1_2_1_22_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.81.17.5546"},{"key":"e_1_2_1_23_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.85.18.6914"},{"key":"e_1_2_1_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/0167-4889(90)90136-2"},{"key":"e_1_2_1_25_2","doi-asserted-by":"crossref","first-page":"3717","DOI":"10.4049\/jimmunol.140.11.3717","volume":"140","author":"Page D. 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