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Three grade IV glioblastomas and one grade II astrocytoma showed amplification. We could also localize the <jats:italic>MET<\/jats:italic> amplicon to dmins in glioblastoma TX3095 by fluorescence in situ hybridization.<\/jats:p>","DOI":"10.1002\/gcc.2870120111","type":"journal-article","created":{"date-parts":[[2007,2,22]],"date-time":"2007-02-22T00:14:23Z","timestamp":1172103263000},"page":"63-65","source":"Crossref","is-referenced-by-count":34,"title":["Amplification of the <i>met<\/i> gene in glioma"],"prefix":"10.1002","volume":"12","author":[{"given":"Ulrike","family":"Fischer","sequence":"first","affiliation":[]},{"given":"Hans\u2010W.","family":"M\u00fcller","sequence":"additional","affiliation":[]},{"given":"Hans\u2010P.","family":"Sattler","sequence":"additional","affiliation":[]},{"given":"Klaus D.","family":"Zang","sequence":"additional","affiliation":[]},{"given":"Eckart","family":"Meese","sequence":"additional","affiliation":[]},{"given":"Klaus","family":"Feiden","sequence":"additional","affiliation":[]}],"member":"311","published-online":{"date-parts":[[2006,7,14]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.87.11.4256"},{"key":"e_1_2_1_3_1","first-page":"27","article-title":"Amplified genes in human gliomas","volume":"4","author":"Collins VP","year":"1993","journal-title":"Semin Cancer Biol"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0165-1110(92)90016-3"},{"key":"e_1_2_1_5_1","doi-asserted-by":"crossref","first-page":"1213","DOI":"10.1073\/pnas.87.3.1213","article-title":"Systematic screening of yeast artificial chromosome libraries by use of the polymerase chain reaction","volume":"87","author":"Green ED","year":"1990","journal-title":"Proc Natl Acad Sci USA"},{"key":"e_1_2_1_6_1","doi-asserted-by":"crossref","first-page":"1614","DOI":"10.1093\/clinchem\/36.9.1614","article-title":"Characterization and rapid diagnostic analysis of DNA polymorphisms closely linked to the cystic fibrosis locus","volume":"36","author":"Horn GT","year":"1990","journal-title":"Clin Chem"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005072-199201000-00010"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.3563490"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/313144a0"},{"key":"e_1_2_1_10_1","first-page":"2736","article-title":"Amplification and overexpression of the MDM2 gene in a subset of human malignant gliomas without p53 mutations","volume":"53","author":"Reifenberger G","year":"1993","journal-title":"Cancer Res"},{"key":"e_1_2_1_11_1","volume-title":"Molecular cloning: A Laboratory Manual","author":"Sambrook J","year":"1989"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.2910560114"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198510313131802"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.3798106"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/318382a0"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.84.19.6899"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/0959-8049(93)90460-W"},{"key":"e_1_2_1_18_1","first-page":"577","article-title":"Two independent amplification events on chromosome 7 in glioma: Amplification of the epidermal growth factor receptor gene and amplification of the oncogene MET","volume":"14","author":"Wullich B","year":"1994","journal-title":"Anticancer Res"}],"container-title":["Genes, Chromosomes and Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fgcc.2870120111","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/gcc.2870120111","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,25]],"date-time":"2023-10-25T16:45:56Z","timestamp":1698252356000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/gcc.2870120111"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1995,1]]},"references-count":17,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1995,1]]}},"alternative-id":["10.1002\/gcc.2870120111"],"URL":"https:\/\/doi.org\/10.1002\/gcc.2870120111","archive":["Portico"],"relation":{},"ISSN":["1045-2257","1098-2264"],"issn-type":[{"value":"1045-2257","type":"print"},{"value":"1098-2264","type":"electronic"}],"subject":[],"published":{"date-parts":[[1995,1]]}}}