{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,17]],"date-time":"2025-09-17T15:00:55Z","timestamp":1758121255179,"version":"3.30.0"},"reference-count":21,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":12237,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[1982,3]]},"abstract":"<jats:sec>\n            <jats:title\/>\n            <jats:p>A series of 80 patients with chronic lobular hepatitis (CLH) was reviewed clinically and histologically to demonstrate etiology, clinical presentation, course, and prognosis of this disorder. Data from our study indicate that CLH in Taiwan is a disease of viral origin, mostly hepatitis B (67.5%) and some non\u2013A, non\u2013B. It occurs predominantly in young males (81.3%); frequently commences as acute viral hepatitis (57.5%); and has clinical and laboratory features similar to convalescent viral hepatitis or even indistinguishable from full\u2013blown acute viral hepatitis. Clinical and histological follow\u2013up study indicate that CLH may extend for several years with remissions and relapses. No evidence of progression to cirrhosis was observed at least in a 4\u00bd\u2013year period of follow\u2013up. It is concluded that CLH is a persistent but nonprogressive disease although the number of non\u2013A, non\u2013B CLH is too small to ascertain its nonprogressive course. The prognosis is generally good, and no specific therapy is required.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1002\/hep.1840020213","type":"journal-article","created":{"date-parts":[[2010,7,5]],"date-time":"2010-07-05T12:41:55Z","timestamp":1278333715000},"page":"258S-262S","update-policy":"http:\/\/dx.doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":34,"title":["Chronic Lobular Hepatitis: A Clinicopathological and Prognostic Study"],"prefix":"10.1097","volume":"2","author":[{"given":"Yun-Fan","family":"Liaw","sequence":"first","affiliation":[]},{"given":"Chia-Ming","family":"Chu","sequence":"additional","affiliation":[]},{"given":"Tong-Jong","family":"Chen","sequence":"additional","affiliation":[]},{"given":"Deng-Yn","family":"Lin","sequence":"additional","affiliation":[]},{"given":"Chi-Sin","family":"Chang-Chien","sequence":"additional","affiliation":[]},{"given":"Cheng-Shyong","family":"Wu","sequence":"additional","affiliation":[]}],"member":"276","reference":[{"key":"10.1002\/hep.1840020213-BIB1|cit1","doi-asserted-by":"crossref","first-page":"1154","DOI":"10.1056\/NEJM197105202842011","article-title":"The vocabulary of chronic hepatitis","volume":"284","author":"Popper","year":"1971","journal-title":"N Engl J Med"},{"volume-title":"Diseases of the liver and biliary tract. 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A histological and etiological study","volume":"80","author":"Liaw","year":"1981","journal-title":"J Formosan Med Assoc"},{"key":"10.1002\/hep.1840020213-BIB14|cit14","first-page":"694","article-title":"Hepatitis A virus infection in Taiwan","volume":"79","author":"Wu","year":"1980","journal-title":"J Formosan Med Assoc"},{"key":"10.1002\/hep.1840020213-BIB15|cit15","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1097\/00000441-197507000-00004","article-title":"Viral hepatitis: a pathologic spectrum","volume":"270","author":"Peters","year":"1975","journal-title":"Am J Med Sci"},{"key":"10.1002\/hep.1840020213-BIB16|cit16","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1016\/S0140-6736(78)91567-2","article-title":"Hepatitis \u201cC\u201d antigen in non-A, non-B post-transfusion hepatitis","volume":"2","author":"Shirachi","year":"1978","journal-title":"Lancet"},{"key":"10.1002\/hep.1840020213-BIB17|cit17","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1093\/infdis\/139.5.511","article-title":"Non-B hepatitis in Japanese recipients of blood transfusions: clinical and serologic studies after the introduction of laboratory screening of donor blood for hepatitis B surface antigen","volume":"139","author":"Tateda","year":"1979","journal-title":"J Infect Dis"},{"key":"10.1002\/hep.1840020213-BIB18|cit18","doi-asserted-by":"crossref","first-page":"539","DOI":"10.7326\/0003-4819-92-4-539","article-title":"Post-transfusion hepatitis: current perspectives","volume":"92","author":"Aach","year":"1980","journal-title":"Ann Intern Med"},{"key":"10.1002\/hep.1840020213-BIB19|cit19","first-page":"423","article-title":"Hepatitis B virus infection and chronic liver disease in Taiwan","volume":"25","author":"Chen","year":"1978","journal-title":"Acta Hepato-Gastroenterol"},{"key":"10.1002\/hep.1840020213-BIB20|cit20","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1136\/gut.15.7.581","article-title":"Chronic hepatitis","volume":"15","author":"Sherlock","year":"1974","journal-title":"Gut"},{"key":"10.1002\/hep.1840020213-BIB21|cit21","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1136\/gut.20.5.372","article-title":"Chronic persistent hepatitis: hepatitis B virus markers and histological follow-up","volume":"20","author":"Chadwick","year":"1979","journal-title":"Gut"}],"container-title":["Hepatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fhep.1840020213","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.lww.com\/01515467-198203000-00012","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T11:01:07Z","timestamp":1733050867000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/01515467-198203000-00012"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1982,3]]},"references-count":21,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1982]]}},"URL":"https:\/\/doi.org\/10.1002\/hep.1840020213","relation":{},"ISSN":["0270-9139"],"issn-type":[{"type":"print","value":"0270-9139"}],"subject":[],"published":{"date-parts":[[1982,3]]}}}