{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,5,10]],"date-time":"2024-05-10T08:55:45Z","timestamp":1715331345923},"reference-count":17,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2006,7,17]],"date-time":"2006-07-17T00:00:00Z","timestamp":1153094400000},"content-version":"vor","delay-in-days":9864,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intl Journal of Cancer"],"published-print":{"date-parts":[[1979,7,15]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Herpesvirus papio<\/jats:italic> (HVP) is an indigenous B\u2010lymphotropic virus of baboons (<jats:italic>Papio sp.<\/jats:italic>) present in latent form in baboon lymphoblastoid cell lines. It shares cross\u2010reacting viral capsid and early antigens with the Epstein\u2010Barr virus (EBV), and HVP DNA and EBV DNA show partial sequence homology. EBV\u2010specific complementary RNA was employed here as a probe to investigate the physical state of the HVP DNA component in baboon lymphoblastoid cells after fractionation of cellular DNA by density gradient centrifugation. Five virus\u2010producing cultures contained both free and integrated HVP DNA sequences while one non\u2010producing cell line had two or three viral genome equivalents per cell in an apparently integrated form. Further analysis of one virus\u2010producing line showed that the free HVP DNA fraction was composed of both linear and circular viral DNA. Contour length measurements of HVP circular DNA molecules by electron microscopy revealed that they were similar in length to the EBV circular DNA present in human lymphoblastoid cells.<\/jats:p>","DOI":"10.1002\/ijc.2910240113","type":"journal-article","created":{"date-parts":[[2007,2,19]],"date-time":"2007-02-19T17:45:07Z","timestamp":1171907107000},"page":"75-79","source":"Crossref","is-referenced-by-count":6,"title":["<i>Herpesvirus papio<\/i>: State and properties of intracellular viral DNA in baboon lymphoblastoid cell lines"],"prefix":"10.1002","volume":"24","author":[{"given":"Lawrence","family":"Falk","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomas","family":"Lindahl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gunnar","family":"Bjursell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George","family":"Klein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,7,17]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1128\/jvi.25.3.710-718.1978","article-title":"Integrated viral DNA sequences in Epstein\u2010Barr virus\u2010converted human lymphoma lines","volume":"25","author":"Andersson\u2010Anvret M.","year":"1978","journal-title":"J. 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