{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,26]],"date-time":"2025-06-26T18:43:03Z","timestamp":1750963383594},"reference-count":11,"publisher":"Wiley","issue":"2-3","license":[{"start":{"date-parts":[[2005,10,20]],"date-time":"2005-10-20T00:00:00Z","timestamp":1129766400000},"content-version":"vor","delay-in-days":3794,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Imaging Syst Tech"],"published-print":{"date-parts":[[1995,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We explored a number of theoretical and practical approaches used to understand and optimize contrast to noise of the versatile <jats:italic>T<\/jats:italic><jats:sub>1<\/jats:sub> based perfusion model. The interplay between tissue <jats:italic>T<\/jats:italic><jats:sub>1<\/jats:sub> and blood <jats:italic>T<\/jats:italic><jats:sub>1<\/jats:sub> was investigated. We also provided a succinct evaluation of the several popular <jats:italic>T<\/jats:italic><jats:sub>1<\/jats:sub> based methods currently applied to measure flow and flow change.<\/jats:p>","DOI":"10.1002\/ima.1850060206","type":"journal-article","created":{"date-parts":[[2007,3,5]],"date-time":"2007-03-05T23:32:18Z","timestamp":1173137538000},"page":"171-174","source":"Crossref","is-referenced-by-count":10,"title":["An intuitive guide to the <i>T<\/i><sub>1<\/sub> based perfusion model"],"prefix":"10.1002","volume":"6","author":[{"given":"David A.","family":"Chesler","sequence":"first","affiliation":[]},{"given":"Kenneth K.","family":"Kwong","sequence":"additional","affiliation":[]}],"member":"311","published-online":{"date-parts":[[2005,10,20]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.1910230106"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.89.1.212"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.89.12.5675"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.192.2.8029425"},{"key":"e_1_2_1_6_2","unstructured":"K. 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P.Koretsky. \u201cMeasurement by arterial spin labeling of the effects of cerebral blood flow on water as a freely diffusable perfusion tracer \u201d in Second Meeting of the Society of Magnetic Resonance San Francisco 1994 p.280."},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.1910330310"}],"container-title":["International Journal of Imaging Systems and Technology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fima.1850060206","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ima.1850060206","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,31]],"date-time":"2023-08-31T07:29:53Z","timestamp":1693466993000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ima.1850060206"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1995,6]]},"references-count":11,"journal-issue":{"issue":"2-3","published-print":{"date-parts":[[1995,6]]}},"alternative-id":["10.1002\/ima.1850060206"],"URL":"https:\/\/doi.org\/10.1002\/ima.1850060206","archive":["Portico"],"relation":{},"ISSN":["0899-9457","1098-1098"],"issn-type":[{"value":"0899-9457","type":"print"},{"value":"1098-1098","type":"electronic"}],"subject":[],"published":{"date-parts":[[1995,6]]}}}