{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,7]],"date-time":"2023-10-07T07:15:15Z","timestamp":1696662915852},"reference-count":30,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2014,11,18]],"date-time":"2014-11-18T00:00:00Z","timestamp":1416268800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Imaging Syst Tech"],"published-print":{"date-parts":[[2014,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>Since both Parkinson's disease with dementia (PDD) and subcortical ischemic vascular dementia (SIVaD) are subcortical dementia syndromes and have similar patterns of cognitive dysfunction, it is difficult to accurately differentiate between these in their early phases using neuropsychological tests. The purpose of this study was to investigate differences in the cerebral perfusion pattern of patients with SIVaD and PDD at the earliest stages using single photon emission computed tomography (SPECT). We, consecutively, recruited 24 patients with mild PDD, 28 patients with mild probable AD, and 33 age\u2010matched healthy subjects. All subjects underwent Tc\u201099m HMPAO perfusion SPECT and general neuropsychological tests. Brain SPECT images were analyzed using the statistical parametric mapping program. There was more significant hypoperfusion in the right cuneus, fusiform gyrus and lingual gyrus in the occipital lobe, right middle temporal gyrus, right postcentral gyrus, and right cerebellar tonsil in PDD compared with the SIVaD group. Conversely, significant hypoperfusion was observed in the bilateral brain stem, limbic system and posterior cingulate gyrus in SIVaD compared with the PDD group. This study suggests that parieto\u2010occipital hypoperfusion in PDD and hypoperfusion of the brain stem and limbic system in SIVaD are likely useful to differentiate between mild PDD and SIVaD.<\/jats:p>","DOI":"10.1002\/ima.22107","type":"journal-article","created":{"date-parts":[[2014,11,18]],"date-time":"2014-11-18T11:50:19Z","timestamp":1416311419000},"page":"306-312","source":"Crossref","is-referenced-by-count":1,"title":["Analysis of cerebral blood flow in Parkinson's disease with dementia versus subcortical ischemic vascular dementia using single photon emission computed tomography"],"prefix":"10.1002","volume":"24","author":[{"given":"Tae\u2010Won","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Neurology College of Medicine, The Cathollic University of Korea Seoul South Korea"}]},{"given":"Yong\u2010An","family":"Chung","sequence":"additional","affiliation":[{"name":"Department of Radiology Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea Incheon South Korea"},{"name":"Department of Neuroscience Center Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea Incheon South Korea"}]},{"given":"In\u2010Uk","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Neurology College of Medicine, The Cathollic University of Korea Seoul South Korea"},{"name":"Department of Neuroscience Center Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea Incheon South Korea"}]},{"given":"Kwang\u2010Soo","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Neurology College of Medicine, The Cathollic University of Korea Seoul South Korea"}]}],"member":"311","published-online":{"date-parts":[[2014,11,18]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-7091-6842-4_3"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/NRL.0b013e31815b0de2"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0197-4580(02)00065-9"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1037\/1040-3590.3.2.168"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/1531-8249(200002)47:2<145::AID-ANA3>3.0.CO;2-P"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.21507"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.2000.tb06376.x"},{"key":"e_1_2_5_9_1","first-page":"23","article-title":"Research criteria for subcortical vascular dementia in clinical trials","volume":"59","author":"Erkinjuntti T.","year":"2000","journal-title":"J Neural Transm Suppl"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/gps.1359"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1053-8119(03)00364-1"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.1910330508"},{"key":"e_1_2_5_13_1","first-page":"61","article-title":"Distinctive cognitive profiles in Alzheimer's disease and subcortical vascular dementia","volume":"75","author":"Graham N.L.","year":"2004","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.21956"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.55.3.181"},{"key":"e_1_2_5_16_1","first-page":"1583","article-title":"SPECT image analysis using statistical parametric mapping in patients with Parkinson's disease","volume":"40","author":"Imon Y.","year":"1999","journal-title":"J Nucl Med"},{"key":"e_1_2_5_17_1","first-page":"300","article-title":"A validity study on the Korean minimental state examination (K\u2010MMSE) in dementia patients","volume":"15","author":"Kang Y.","year":"1997","journal-title":"J Korean Neurol Assoc"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jcbfm.9600296"},{"key":"e_1_2_5_19_1","doi-asserted-by":"crossref","first-page":"315","DOI":"10.3233\/JAD-2012-111832","article-title":"Cortical thinning in subcortical vascular dementia with negative 11C\u2010PiB PET","volume":"31","author":"Kim C.H.","year":"2012","journal-title":"J Alzheimers Dis"},{"key":"e_1_2_5_20_1","first-page":"1621","article-title":"Assessment of demented patients by dynamic SPECT of inhaled xenon\u2010133","volume":"29","author":"Komatani A.","year":"1988","journal-title":"J Nucl Med"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.46.3.678"},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.57.2.180"},{"key":"e_1_2_5_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02988596"},{"key":"e_1_2_5_24_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000187889.17253.b1"},{"key":"e_1_2_5_25_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.43.2.250"},{"key":"e_1_2_5_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.parkreldis.2009.05.012"},{"key":"e_1_2_5_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1552-6569.2008.00293.x"},{"key":"e_1_2_5_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2006.07.008"},{"key":"e_1_2_5_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-510X(02)00291-5"},{"key":"e_1_2_5_30_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.21.12.1694"},{"key":"e_1_2_5_31_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12149-011-0547-2"}],"container-title":["International Journal of Imaging Systems and Technology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fima.22107","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ima.22107","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,6]],"date-time":"2023-10-06T05:08:54Z","timestamp":1696568934000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ima.22107"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,11,18]]},"references-count":30,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2014,12]]}},"alternative-id":["10.1002\/ima.22107"],"URL":"https:\/\/doi.org\/10.1002\/ima.22107","archive":["Portico"],"relation":{},"ISSN":["0899-9457","1098-1098"],"issn-type":[{"value":"0899-9457","type":"print"},{"value":"1098-1098","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,11,18]]}}}