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One\u2010hundred percent morselized HA\u2010TCP, a 50:50 mixture of morselized HA\u2010TCP, and autogenous cancellous bone, and 100% autogenous cancellous bone were used to bridge 2.5\u2010cm defects in the left ulnae of three groups of six dogs each. At 24 weeks the ulnae were explanted and studied by radiography, microradiography, mechanical testing, and histology. Pure HA\/TCP was not osteoinductive, and four of six ulnae in this group progressed to a fibrous nonunion. The HA\/TCP\u2010cancellous bone mixture and pure cancellous bone were approximately equal in effect, leading to good callus formation at 4 weeks and strong bony union by 24 weeks, with no evidence of bioincompatibility. Morselized HA\/TCP promises to be useful as a graft extender when mixed with autogenous cancellous bone.<\/jats:p>","DOI":"10.1002\/jor.1100050307","type":"journal-article","created":{"date-parts":[[2005,2,24]],"date-time":"2005-02-24T13:05:03Z","timestamp":1109250303000},"page":"356-365","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":128,"title":["The evaluation of a biphasic calcium phosphate ceramic for use in grafting long\u2010bone diaphyseal defects"],"prefix":"10.1002","volume":"5","author":[{"given":"D. C.","family":"Moore","sequence":"first","affiliation":[]},{"given":"M. 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