{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T17:08:55Z","timestamp":1760980135670,"version":"build-2065373602"},"reference-count":55,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2004,10,12]],"date-time":"2004-10-12T00:00:00Z","timestamp":1097539200000},"content-version":"vor","delay-in-days":4302,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Movement Disorders"],"published-print":{"date-parts":[[1993,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>At least five receptors for dopamine (D<jats:sub>1<\/jats:sub>\u2013D<jats:sub>5<\/jats:sub>) have been recognised from molecular biological studies, and their pharmacological properties and brain localisations have been determined. The D<jats:sub>1<\/jats:sub> and D<jats:sub>2<\/jats:sub> subtypes are the principal subtypes in brain, and their cellular localisations in the caudate nucleus and putamen have been determined. With recent advances in the understanding of basal ganglia neuronal function, these localisation data enable insights into the mode of action of drugs used at present and in the futue to treat Parkinson's disease.<\/jats:p>","DOI":"10.1002\/mds.870080303","type":"journal-article","created":{"date-parts":[[2004,12,31]],"date-time":"2004-12-31T10:07:02Z","timestamp":1104487622000},"page":"263-270","source":"Crossref","is-referenced-by-count":48,"title":["Dopamine receptors in the basal ganglia: Relevance to parkinson's disease"],"prefix":"10.1002","volume":"8","author":[{"given":"Philip G.","family":"Strange","sequence":"first","affiliation":[]}],"member":"311","published-online":{"date-parts":[[2004,10,12]]},"reference":[{"volume-title":"Brain biochemistry and brain disorders","year":"1992","author":"Strange PG","key":"e_1_2_1_2_2"},{"key":"e_1_2_1_3_2","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1042\/bst0200126","article-title":"Studies on the structure and function of D2 dopamine receptors","volume":"20","author":"Strange PG","year":"1992","journal-title":"Biochem Soc Trans"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/0165-6147(92)90025-2"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.1993.tb05863.x"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/0166-2236(90)90106-K"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.2147780"},{"key":"e_1_2_1_8_2","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/0306-4522(92)90096-K","article-title":"D1 and D2 dopamine receptors differentially regulate c\u2010fos expression in striatonigral and striatopallidal neurones","volume":"49","author":"Robertson GS","year":"1992","journal-title":"Neuroscience"},{"key":"e_1_2_1_9_2","first-page":"231","article-title":"Comparison of the distributions of D1 and D2 dopamine receptor mRNAs in rat brain","volume":"5","author":"Meador\u2010Woodruff SH","year":"1991","journal-title":"Neuropsychopharmacology"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/0169-328X(91)90086-D"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.ne.09.030186.002041"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0079-6123(08)62678-3"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/0166-2236(90)90109-N"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/0306-4522(84)90294-X"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/0166-2236(89)90074-X"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/0166-2236(90)90182-A"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00237874"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1042\/bj2490309"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198804073181402"},{"key":"e_1_2_1_20_2","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/0166-2236(90)90110-V","article-title":"Primate models of movement disorders of basal ganglia origin","volume":"13","author":"De Long MR","year":"1990","journal-title":"Trends Neurosci"},{"key":"e_1_2_1_21_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.53.2.96"},{"key":"e_1_2_1_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/0163-7258(87)90063-5"},{"key":"e_1_2_1_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/0166-2236(92)90034-6"},{"key":"e_1_2_1_24_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00172952"},{"key":"e_1_2_1_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/0014-2999(91)90304-9"},{"key":"e_1_2_1_26_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.40.6.927"},{"key":"e_1_2_1_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/0014-2999(90)90642-J"},{"key":"e_1_2_1_28_2","doi-asserted-by":"publisher","DOI":"10.1016\/0014-2999(88)90322-6"},{"key":"e_1_2_1_29_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01244638"},{"key":"e_1_2_1_30_2","doi-asserted-by":"publisher","DOI":"10.1016\/0014-2999(91)90508-N"},{"key":"e_1_2_1_31_2","doi-asserted-by":"publisher","DOI":"10.1097\/00002826-199208000-00005"},{"key":"e_1_2_1_32_2","doi-asserted-by":"publisher","DOI":"10.1002\/mds.870040307"},{"key":"e_1_2_1_33_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.39.6.856"},{"key":"e_1_2_1_34_2","doi-asserted-by":"publisher","DOI":"10.1002\/mds.870070309"},{"key":"e_1_2_1_35_2","doi-asserted-by":"publisher","DOI":"10.1002\/mds.870070108"},{"key":"e_1_2_1_36_2","doi-asserted-by":"publisher","DOI":"10.1038\/347146a0"},{"key":"e_1_2_1_37_2","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(91)91456-B"},{"key":"e_1_2_1_38_2","doi-asserted-by":"publisher","DOI":"10.1016\/0306-4522(80)90048-2"},{"key":"e_1_2_1_39_2","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(91)92565-J"},{"key":"e_1_2_1_40_2","doi-asserted-by":"publisher","DOI":"10.1002\/mds.870050203"},{"key":"e_1_2_1_41_2","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1016\/S0022-3565(25)20396-2","article-title":"Effects of D1 and D2 agonists and antagonists on dyskinesias produced by l\u2010DOPA in 1\u2010methyl, 4\u2010phenyl, 1, 2, 3, 6 tetrahydropyridine treated monkeys","volume":"259","author":"Gomez Mancilla B","year":"1991","journal-title":"J Pharmacol Exp Ther"},{"key":"e_1_2_1_42_2","doi-asserted-by":"publisher","DOI":"10.1016\/0014-2999(89)90790-5"},{"key":"e_1_2_1_43_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.1990.tb05803.x"},{"key":"e_1_2_1_44_2","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/S0026-895X(25)09456-8","article-title":"Agonist induced desensitisation of D1\u2010dopamine receptos linked to adenylyl cyclase activity in cultured NS20Y neuroblastoma cells","volume":"38","author":"Barton AC","year":"1990","journal-title":"Mol Pharmacol"},{"key":"e_1_2_1_45_2","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1016\/S0026-895X(25)11059-6","article-title":"Agonist induced desensitisation of D2 dopamine receptors in human Y\u201079 retinoblastoma cells","volume":"39","author":"Barton AC","year":"1991","journal-title":"Mol Pharmacol"},{"key":"e_1_2_1_46_2","doi-asserted-by":"publisher","DOI":"10.1096\/fasebj.4.10.2197154"},{"key":"e_1_2_1_47_2","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(91)90554-9"},{"key":"e_1_2_1_48_2","first-page":"144","article-title":"In vivo and in vitro studies of the dopaminergic system in movement disorders","volume":"4","author":"Playford ED","year":"1992","journal-title":"Cerebrovasc Brain Metab Rev"},{"key":"e_1_2_1_49_2","doi-asserted-by":"publisher","DOI":"10.1016\/0014-2999(90)94802-5"},{"key":"e_1_2_1_50_2","doi-asserted-by":"publisher","DOI":"10.1002\/jnr.490270409"},{"key":"e_1_2_1_51_2","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1016\/0006-2952(92)90227-A","article-title":"The third dopamine receptor (D3) as a novel target for antipsychotics","volume":"43","author":"Sokoloff P","year":"1992","journal-title":"Biochem Pharmacol"},{"key":"e_1_2_1_52_2","doi-asserted-by":"publisher","DOI":"10.1038\/347072a0"},{"key":"e_1_2_1_53_2","doi-asserted-by":"publisher","DOI":"10.1038\/350614a0"},{"key":"e_1_2_1_54_2","first-page":"501","article-title":"cDNA cloning of the human dopaminergic D3 receptor and chromosome identification","volume":"311","author":"Giros B","year":"1990","journal-title":"C R Acad Sci III"},{"key":"e_1_2_1_55_2","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1038\/350610a0","article-title":"Cloning of the gene for a human D4 receptor with high affinity for the antipsychotic clozapine","volume":"350","author":"Van Tol HHM","year":"1991","journal-title":"Nature"},{"key":"e_1_2_1_56_2","first-page":"137","article-title":"The rat dopamine D4 receptor: sequence, gene structure and demonstration of expression in the cardiovascular system","volume":"4","author":"O'Malley KL","year":"1992","journal-title":"New Biol"}],"container-title":["Movement Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmds.870080303","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mds.870080303","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T12:28:54Z","timestamp":1760963334000},"score":1,"resource":{"primary":{"URL":"https:\/\/movementdisorders.onlinelibrary.wiley.com\/doi\/10.1002\/mds.870080303"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1993,1]]},"references-count":55,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1993,1]]}},"alternative-id":["10.1002\/mds.870080303"],"URL":"https:\/\/doi.org\/10.1002\/mds.870080303","archive":["Portico"],"relation":{},"ISSN":["0885-3185","1531-8257"],"issn-type":[{"type":"print","value":"0885-3185"},{"type":"electronic","value":"1531-8257"}],"subject":[],"published":{"date-parts":[[1993,1]]}}}