{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T10:44:37Z","timestamp":1762339477117},"reference-count":24,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2001,11,15]],"date-time":"2001-11-15T00:00:00Z","timestamp":1005782400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Magnetic Resonance in Med"],"published-print":{"date-parts":[[2001,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>In this study, diffusion\u2010weighted images of the human prostate were successfully obtained, enabling quantification of apparent diffusion coefficients (ADCs) in normal and pathologic regions. A dual acquisition fast spin\u2010echo sequence was used for accurate <jats:italic>T<\/jats:italic><jats:sub>2<\/jats:sub> calculation. <jats:italic>T<\/jats:italic><jats:sub>2<\/jats:sub> values were significantly higher in the peripheral zone than the central gland (<jats:italic>P<\/jats:italic> = 0.015). No significant correlations were found in either normal or pathologic tissue between ADC values and relaxation rates for all three gradient directions and the orientationally averaged water diffusion coefficient. Evidence suggesting that diffusional anisotropy is present in normal prostatic tissue is also detailed, with significant differences noted between the z\u2010component and both the x\u2010 and y\u2010components of the ADC for peripheral zone (<jats:italic>P<\/jats:italic> &lt; 0.040) and central gland (<jats:italic>P<\/jats:italic> &lt; 0.001). Magn Reson Med 46:1054\u20131058, 2001. \u00a9 2001 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/mrm.1298","type":"journal-article","created":{"date-parts":[[2002,8,25]],"date-time":"2002-08-25T19:50:10Z","timestamp":1030305010000},"page":"1054-1058","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":175,"title":["Comparison of quantitative <i>T<\/i><sub>2<\/sub> mapping and diffusion\u2010weighted imaging in the normal and pathologic prostate"],"prefix":"10.1002","volume":"46","author":[{"given":"Peter","family":"Gibbs","sequence":"first","affiliation":[]},{"given":"Daniel J.","family":"Tozer","sequence":"additional","affiliation":[]},{"given":"Gary P.","family":"Liney","sequence":"additional","affiliation":[]},{"given":"Lindsay W.","family":"Turnbull","sequence":"additional","affiliation":[]}],"member":"311","published-online":{"date-parts":[[2001,11,15]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.172.1.2472644"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02592242"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.215.2.r00ap09445"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0009-9260(05)83288-X"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/00004728-199503000-00013"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1522-2586(199902)9:2<311::AID-JMRI24>3.0.CO;2-W"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1053\/crad.1999.0327"},{"key":"e_1_2_5_9_2","unstructured":"van DorstenFA van der GraafM EngelbrechtM van LeendersGJLH de la RosetteJJMCH HuismanHJ BarentszJO HeerschapA.Proton MR spectroscopic imaging (MRSI) and dynamic Gd\u2010enhanced MRI of the human prostate. 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