{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T22:51:39Z","timestamp":1773787899932,"version":"3.50.1"},"reference-count":44,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2001,4,19]],"date-time":"2001-04-19T00:00:00Z","timestamp":987638400000},"content-version":"vor","delay-in-days":18,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["NMR in Biomedicine"],"published-print":{"date-parts":[[2001,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>This review describes magnetization transfer (MT) contrast in magnetic resonance imaging. A qualitative description of how MT works is provided along with experimental evidence that leads to a quantitative model for MT in tissues. The implementation of MT saturation in imaging sequences and the interpretation of the MT\u2010induced signal change in terms of exchange processes and direct effects are presented. Finally, highlights of clinical uses of MT are outlined and future directions for investigation proposed. Copyright \u00a9 2001 John Wiley &amp; Sons, Ltd.<\/jats:p><jats:p><jats:def-list>\n<jats:title><jats:bold>Abbreviations used:<\/jats:bold><\/jats:title>\n<jats:def-item>\n<jats:term>B<jats:sub>eff<\/jats:sub><\/jats:term>\n<jats:def>\n\n<jats:p>effective magnetic field<\/jats:p>\n<\/jats:def>\n<\/jats:def-item>\n<jats:def-item>\n<jats:term>CRMG<\/jats:term>\n<jats:def>\n\n<jats:p>Carr\u2013Purcell\u2013Meiboom\u2013Gill<\/jats:p>\n<\/jats:def>\n<\/jats:def-item>\n<jats:def-item>\n<jats:term>CW<\/jats:term>\n<jats:def>\n\n<jats:p>continuous wave<\/jats:p>\n<\/jats:def>\n<\/jats:def-item>\n<jats:def-item>\n<jats:term>FAIR<\/jats:term>\n<jats:def>\n\n<jats:p>flow sensitive alternating inversion recovery<\/jats:p>\n<\/jats:def>\n<\/jats:def-item>\n<jats:def-item>\n<jats:term>Gd\u2010DTPA<\/jats:term>\n<jats:def>\n\n<jats:p>gadolinium diethylenetriminepentaacetic acid<\/jats:p>\n<\/jats:def>\n<\/jats:def-item>\n<jats:def-item>\n<jats:term>MRA<\/jats:term>\n<jats:def>\n\n<jats:p>magnetic resonance angiography<\/jats:p>\n<\/jats:def>\n<\/jats:def-item>\n<jats:def-item>\n<jats:term>MRI<\/jats:term>\n<jats:def>\n\n<jats:p>magnetic resonance imaging<\/jats:p>\n<\/jats:def>\n<\/jats:def-item>\n<jats:def-item>\n<jats:term>MS<\/jats:term>\n<jats:def>\n\n<jats:p>multiple sclerosis<\/jats:p>\n<\/jats:def>\n<\/jats:def-item>\n<jats:def-item>\n<jats:term>MT<\/jats:term>\n<jats:def>\n\n<jats:p>magnetization transfer<\/jats:p>\n<\/jats:def>\n<\/jats:def-item>\n<jats:def-item>\n<jats:term>MTR<\/jats:term>\n<jats:def>\n\n<jats:p>magnetization transfer ratio<\/jats:p>\n<\/jats:def>\n<\/jats:def-item>\n<jats:def-item>\n<jats:term>RF<\/jats:term>\n<jats:def>\n\n<jats:p>radio frequency<\/jats:p>\n<\/jats:def>\n<\/jats:def-item>\n<jats:def-item>\n<jats:term>SAR<\/jats:term>\n<jats:def>\n\n<jats:p>specific absorption rate.<\/jats:p>\n<\/jats:def>\n<\/jats:def-item>\n<\/jats:def-list><\/jats:p>","DOI":"10.1002\/nbm.683","type":"journal-article","created":{"date-parts":[[2002,9,10]],"date-time":"2002-09-10T18:53:09Z","timestamp":1031683989000},"page":"57-64","source":"Crossref","is-referenced-by-count":797,"title":["Magnetization transfer in MRI: a review"],"prefix":"10.1002","volume":"14","author":[{"given":"R. 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