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This issue has consequences for the medical field, which only has a nascent understanding of how to identify and meet this population's health\u2010related needs. Social media sites like Twitter provide new opportunities for transgender people to overcome these barriers by sharing their personal health experiences. Our research employs a computational framework to collect tweets from self\u2010identified transgender users, detect those that are health\u2010related, and identify their information needs. This framework is significant because it provides a macro\u2010scale perspective on an issue that lacks investigation at national or demographic levels. Our findings identified 54 distinct health\u2010related topics that we grouped into 7 broader categories. Further, we found both linguistic and topical differences in the health\u2010related information shared by transgender men (TM) as compared to transgender women (TW). These findings can help inform medical and policy\u2010based strategies for health interventions within transgender communities. Also, our proposed approach can inform the development of computational strategies to identify the health\u2010related information needs of other marginalized populations.<\/jats:p>","DOI":"10.1002\/pra2.2018.14505501023","type":"journal-article","created":{"date-parts":[[2019,2,1]],"date-time":"2019-02-01T16:52:19Z","timestamp":1549039939000},"page":"207-215","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["Characterizing transgender health issues in Twitter"],"prefix":"10.1002","volume":"55","author":[{"given":"Amir","family":"Karami","sequence":"first","affiliation":[{"name":"University of South Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frank","family":"Webb","sequence":"additional","affiliation":[{"name":"University of South Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vanessa L.","family":"Kitzie","sequence":"additional","affiliation":[{"name":"University of South Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,2]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"crossref","unstructured":"Abbar S. 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