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This algorithm yields a unique curved axis which quantifies the folding of the backbone and a full set of helicoidal parameters describing the location of each peptide unit. The parameters obtained form a complete and independent set and can therefore be used for analyzing, comparing, or reconstructing protein backbone geometry. This algorithm has been implemented in a computer program named P\u2010Curve. Several examples of its possible applications are discussed.<\/jats:p>","DOI":"10.1002\/prot.340060105","type":"journal-article","created":{"date-parts":[[2005,5,29]],"date-time":"2005-05-29T01:03:37Z","timestamp":1117328617000},"page":"46-60","source":"Crossref","is-referenced-by-count":107,"title":["Describing protein structure: A general algorithm yielding complete helicoidal parameters and a unique overall axis"],"prefix":"10.1002","volume":"6","author":[{"given":"Heinz","family":"Sklenar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Etchebest","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Lavery","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2004,2,3]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3495(65)86759-5"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0065-3233(08)60520-3"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-2836(80)90052-2"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-2836(77)90207-8"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/bip.360221211"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0065-3233(08)60063-7"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1021\/ma60066a020"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1021\/ma60078a017"},{"key":"e_1_2_1_10_2","first-page":"1259","article-title":"Differential geometry and polymer conformation","volume":"14","author":"Rackovsky S.","year":"1981","journal-title":"III. 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