{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T20:49:27Z","timestamp":1767991767012,"version":"3.49.0"},"reference-count":32,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2017,3,20]],"date-time":"2017-03-20T00:00:00Z","timestamp":1489968000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Applied Clin Med Phys"],"published-print":{"date-parts":[[2017,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Model\u2010based dose calculation algorithms have recently been incorporated into brachytherapy treatment planning systems, and their introduction requires critical evaluation before clinical implementation. Here, we present an experimental evaluation of Oncentra<jats:sup>\u00ae<\/jats:sup> Brachy Advanced Collapsed\u2010cone Engine (ACE) for a multichannel vaginal cylinder (MCVC) applicator using radiochromic film. A uniform dose of 500 cGy was specified to the surface of the MCVC using the TG\u201043 dose formalism under two conditions: (a) with only the central channel loaded or (b) only the peripheral channels loaded. Film measurements were made at the applicator surface and compared to the doses calculated using TG\u201043, standard accuracy ACE (sACE), and high accuracy ACE (hACE). When the central channel of the applicator was used, the film measurements showed a dose increase of (11\u00a0\u00b1\u00a08)% (k\u00a0=\u00a02) above the two outer grooves on the applicator surface. This increase in dose was confirmed with the hACE calculations, but was not confirmed with the sACE calculations at the applicator surface. When the peripheral channels were used, a periodic azimuthal variation in measured dose was observed around the applicator. The sACE and hACE calculations confirmed this variation and agreed within 1% of each other at the applicator surface. Additionally for the film measurements with the central channel used, a baseline dose variation of (10\u00a0\u00b1\u00a04)% (k\u00a0=\u00a02) of the mean dose was observed azimuthally around the applicator surface, which can be explained by offset source positioning in the central channel.<\/jats:p>","DOI":"10.1002\/acm2.12061","type":"journal-article","created":{"date-parts":[[2017,3,20]],"date-time":"2017-03-20T08:46:55Z","timestamp":1489999615000},"page":"16-27","source":"Crossref","is-referenced-by-count":10,"title":["Experimental verification of Advanced Collapsed\u2010cone Engine for use with a multichannel vaginal cylinder applicator"],"prefix":"10.1002","volume":"18","author":[{"given":"Brie","family":"Cawston\u2010Grant","sequence":"first","affiliation":[{"name":"Department of Medical Physics Cross Cancer Institute Edmonton AB T6G 1Z2 Canada"},{"name":"Department of Oncology University of Alberta Edmonton AB T6G 2R3 Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hali","family":"Morrison","sequence":"additional","affiliation":[{"name":"Department of Medical Physics Cross Cancer Institute Edmonton AB T6G 1Z2 Canada"},{"name":"Department of Oncology University of Alberta Edmonton AB T6G 2R3 Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Geetha","family":"Menon","sequence":"additional","affiliation":[{"name":"Department of Medical Physics Cross Cancer Institute Edmonton AB T6G 1Z2 Canada"},{"name":"Department of Oncology University of Alberta Edmonton AB T6G 2R3 Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ron S","family":"Sloboda","sequence":"additional","affiliation":[{"name":"Department of Medical Physics Cross Cancer Institute Edmonton AB T6G 1Z2 Canada"},{"name":"Department of Oncology University of Alberta Edmonton AB T6G 2R3 Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,3,20]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1118\/1.1646040"},{"key":"e_1_2_12_3_1","first-page":"1","volume-title":"ACE: Advanced Collapsed cone Engine (White Paper)","author":"Beaulieu L","year":"2014"},{"key":"e_1_2_12_4_1","first-page":"1","volume-title":"Radiation Dose Reduction in OAR by using the Fletcher CT\/MR Shielded Applicator and Oncentra\u00ae Brachy Advanced Collapsed cone Engine (White Paper)","author":"Mourtada F","year":"2014"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmpb.2016.10.022"},{"key":"e_1_2_12_6_1","unstructured":"Varian Medical Systems.Acuros\u2122 BrachyVision\u2122 algorithm reference guide. 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