{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:16:56Z","timestamp":1786976216624,"version":"build-2736575974"},"reference-count":12,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2017,4,26]],"date-time":"2017-04-26T00:00:00Z","timestamp":1493164800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Applied Clin Med Phys"],"published-print":{"date-parts":[[2017,5]]},"abstract":"Abstract<\/jats:title>\n \n A low modulation factor (\n MF<\/jats:styled-content>\n ) maintaining a good dose distribution contributes to the shortening of the delivery time and efficiency of the treatment plan in helical tomotherapy. The purpose of this study was to reduce the delivery time using initial values and the upper limit values of\n MF<\/jats:styled-content>\n . First, patients with head and neck cancer (293 cases) or prostate cancer (181 cases) treated between June 2011 and July 2015 were included in the analysis of\n MF<\/jats:styled-content>\n values. The initial\n MF<\/jats:styled-content>\n value (\n MF<\/jats:styled-content>\n initial<\/jats:sub>\n ) was defined as the average\n \n MF<\/jats:styled-content>\n <\/jats:italic>\n actual<\/jats:sub>\n value, and the upper limit of the\n MF<\/jats:styled-content>\n value (\n \n MF\n UL<\/jats:sub>\n <\/jats:styled-content>\n ) was defined according the following equation:\u2028MF\n UL<\/jats:sub>\n = 2 \u00d7 standard deviation of\n MF<\/jats:italic>\n actual<\/jats:sub>\n value + the average\n MF<\/jats:italic>\n actual<\/jats:sub>\n <\/jats:p>\n \n Next, a treatment plan was designed for patients with head and neck cancer (62 cases) and prostate cancer (13 cases) treated between December 2015 and June 2016. The average\n \n MF<\/jats:styled-content>\n <\/jats:italic>\n actual<\/jats:sub>\n value for the nasopharynx, oropharynx, hypopharynx, and prostate cases decreased from 2.1 to 1.9 (\n p<\/jats:italic>\n = 0.0006), 1.9 to 1.6 (\n p<\/jats:italic>\n < 0.0001), 2.0 to 1.7 (\n p<\/jats:italic>\n < 0.0001), and 1.8 to 1.6 (\n p<\/jats:italic>\n = 0.0004) by adapting the\n MF<\/jats:styled-content>\n initial<\/jats:sub>\n and the\n \n MF\n UL<\/jats:sub>\n <\/jats:styled-content>\n values, respectively. The average delivery time for the nasopharynx, oropharynx, hypopharynx, and prostate cases also decreased from 19.9 s cm\n \u22121<\/jats:sup>\n to 16.7 s cm\n \u22121<\/jats:sup>\n (\n p<\/jats:italic>\n < 0.0001), 15.0 s cm\n \u22121<\/jats:sup>\n to 13.9 s cm\n \u22121<\/jats:sup>\n (\n p<\/jats:italic>\n = 0.025), 15.1 s cm\n \u22121<\/jats:sup>\n to 13.8 s cm\n \u22121<\/jats:sup>\n (\n p<\/jats:italic>\n = 0.015), and 23.6 s cm\n \u22121<\/jats:sup>\n to 16.9 s cm\n \u22121<\/jats:sup>\n (\n p<\/jats:italic>\n = 0.008) respectively. The delivery time was shortened by the adaptation of\n MF<\/jats:styled-content>\n initial<\/jats:sub>\n and\n \n MF\n UL<\/jats:sub>\n <\/jats:styled-content>\n values with a reduction in the average\n \n MF<\/jats:styled-content>\n <\/jats:italic>\n actual<\/jats:sub>\n for head and neck cancer and prostate cancer cases.\n <\/jats:p>","DOI":"10.1002\/acm2.12075","type":"journal-article","created":{"date-parts":[[2017,4,26]],"date-time":"2017-04-26T04:15:58Z","timestamp":1493180158000},"page":"83-87","source":"Crossref","is-referenced-by-count":12,"title":["Analysis of modulation factor to shorten the delivery time in helical tomotherapy"],"prefix":"10.1002","volume":"18","author":[{"given":"Hidetoshi","family":"Shimizu","sequence":"first","affiliation":[{"name":"Department of Radiation Oncology Aichi Cancer Center Hospital Nagoya Aichi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koji","family":"Sasaki","sequence":"additional","affiliation":[{"name":"Department of radiation therapy education and research Graduate School of Radiological Technology Gunma Prefectural College of Health Sciences Maebashi Gunma Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroyuki","family":"Tachibana","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Aichi Cancer Center Hospital Nagoya Aichi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natsuo","family":"Tomita","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Aichi Cancer Center Hospital Nagoya Aichi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiyoko","family":"Makita","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Aichi Cancer Center Hospital Nagoya Aichi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kuniyasu","family":"Nakashima","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Aichi Cancer Center Hospital Nagoya Aichi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazushi","family":"Yokoi","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Aichi Cancer Center Hospital Nagoya Aichi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takashi","family":"Kubota","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Aichi Cancer Center Hospital Nagoya Aichi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manabu","family":"Yoshimoto","sequence":"additional","affiliation":[{"name":"Department of Radiology Aichi Cancer Center Aichi Hospital Okazaki Aichi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tohru","family":"Iwata","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Aichi Cancer Center Hospital Nagoya Aichi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takeshi","family":"Kodaira","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Aichi Cancer Center Hospital Nagoya Aichi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,4,26]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1118\/1.3462971"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.6009\/jjrt.67.1548"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1118\/1.2044428"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmp.2012.03.007"},{"key":"e_1_2_8_6_1","first-page":"46","article-title":"The current status of intensity modulated radiotherapy in aichi cancer center hospital","volume":"31","author":"Shimizu H","year":"2016","journal-title":"Jpn J Radiother Section Radiol Technol"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1120\/jacmp.v16i5.5282"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1118\/1.3644842"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1118\/1.1896453"},{"key":"e_1_2_8_10_1","unstructured":"2009 R Foundation for Statistical Computing Vienna Austria R Development Core Team R: A language and environment for statistical computing"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1120\/jacmp.v16i2.4964"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1118\/1.4870987"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2009.07.1686"}],"container-title":["Journal of Applied Clinical Medical Physics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Facm2.12075","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aapm.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/acm2.12075","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,25]],"date-time":"2023-09-25T01:22:30Z","timestamp":1695604950000},"score":1,"resource":{"primary":{"URL":"https:\/\/aapm.onlinelibrary.wiley.com\/doi\/10.1002\/acm2.12075"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,4,26]]},"references-count":12,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2017,5]]}},"alternative-id":["10.1002\/acm2.12075"],"URL":"https:\/\/doi.org\/10.1002\/acm2.12075","archive":["Portico"],"relation":{},"ISSN":["1526-9914","1526-9914"],"issn-type":[{"value":"1526-9914","type":"print"},{"value":"1526-9914","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,4,26]]}}}