{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T20:10:24Z","timestamp":1791231024853,"version":"4.1.0"},"reference-count":22,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2020,3,20]],"date-time":"2020-03-20T00:00:00Z","timestamp":1584662400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["aapm.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Applied Clin Med Phys"],"published-print":{"date-parts":[[2020,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and purpose<\/jats:title>\n                    <jats:p>Multiple techniques can be used to assist with more accurate patient setup and monitoring during Stereotactic body radiation therapy (SBRT) treatment. This study analyzes the accuracy of 3D surface mapping with Surface\u2010guided radiation therapy (SGRT) in detecting interfraction setup error and intrafraction motion during SBRT treatments of the lung and abdomen.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>Seventy\u2010one patients with 85 malignant thoracic or abdominal tumors treated with SBRT were analyzed. For initial patient setup, an alternating scheme of kV\/kV imaging or SGRT was followed by cone beam computed tomography (CBCT) for more accurate tumor volumetric localization. The CBCT six degree shifts after initial setup with each method were recorded to assess interfraction setup error. Patients were then monitored continuously with SGRT during treatment. If an intrafractional shift in any direction &gt;2\u00a0mm for longer than 2\u00a0sec was detected by SGRT, then CBCT was repeated and the recorded deltas were compared to those detected by SGRT.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Interfractional shifts after SGRT setup and CBCT were small in all directions with mean values of &lt;5\u00a0mm and &lt;\u00a00.5\u00a0degrees in all directions. Additionally, 25 patients had detected intrafraction motion by SGRT during a total of 34 fractions. This resulted in 25 (73.5%) additional shifts of at least 2\u00a0mm on subsequent CBCT. When comparing the average vector detected shift by SGRT to the resulting vector shift on subsequent CBCT, no significant difference was found between the two.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Surface\u2010guided radiation therapy provides initial setup within 5\u00a0mm for patients treated with SBRT and can be used in place of skin marks or planar kV imaging prior to CBCT. In addition, continuous monitoring with SGRT during treatment was valuable in detecting potentially clinically meaningful intrafraction motion and was comparable in magnitude to shifts from additional CBCT scans. PTV margin reduction may be feasible for SBRT in the lung and abdomen when using SGRT for continuous patient monitoring during treatment.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/acm2.12852","type":"journal-article","created":{"date-parts":[[2020,3,20]],"date-time":"2020-03-20T14:46:20Z","timestamp":1584715580000},"page":"48-55","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":60,"title":["Use of surface\u2010guided radiation therapy in combination with IGRT for setup and intrafraction motion monitoring during stereotactic body radiation therapy treatments of the lung and abdomen"],"prefix":"10.1002","volume":"21","author":[{"given":"John H.","family":"Heinzerling","sequence":"first","affiliation":[{"name":"Levine Cancer Institute Southeast Radiation Oncology Group Atrium Health Charlotte NC USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carnell J.","family":"Hampton","sequence":"additional","affiliation":[{"name":"Levine Cancer Institute Department of Radiation Oncology Atrium Health Charlotte NC USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Myra","family":"Robinson","sequence":"additional","affiliation":[{"name":"Levine Cancer Institute Department of Biostatistics Atrium Health Charlotte NC USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Megan","family":"Bright","sequence":"additional","affiliation":[{"name":"Levine Cancer Institute Department of Radiation Oncology Atrium Health Charlotte NC USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin J","family":"Moeller","sequence":"additional","affiliation":[{"name":"Levine Cancer Institute Southeast Radiation Oncology Group Atrium Health Charlotte NC USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justin","family":"Ruiz","sequence":"additional","affiliation":[{"name":"Levine Cancer 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