{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T11:58:59Z","timestamp":1787313539442,"version":"build-2736575974"},"reference-count":23,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2020,10,26]],"date-time":"2020-10-26T00:00:00Z","timestamp":1603670400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["aapm.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Applied Clin Med Phys"],"published-print":{"date-parts":[[2020,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>Pulmonary perfusion is an important factor for gas exchange. Chest digital dynamic radiography (DDR) by the deep\u2010breathing protocol can evaluate pulmonary perfusion in healthy subjects. However, respiratory artifacts may affect DDR in patients with respiratory diseases. We examined the feasibility of a breath\u2010holding protocol and compared it with the deep\u2010breathing protocol to reduce respiratory artifacts.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and methods<\/jats:title>\n                    <jats:p>A total of 42 consecutive patients with respiratory diseases (32 males; age, 68.6\u00a0\u00b1\u00a012.3\u00a0yr), including 21 patients with chronic obstructive pulmonary disease, underwent chest DDR through the breath\u2010holding protocol and the deep\u2010breathing protocol. Imaging success rate and exposure to radiation were compared. The correlation rate of temporal changes in each pixel value between the lung fields and left cardiac ventricles was analyzed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Imaging success rate was higher with the breath\u2010holding protocol vs the deep\u2010breathing protocol (97% vs 69%, respectively;\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u00a00.0001). The entrance surface dose was lower with the breath\u2010holding protocol (1.09\u00a0\u00b1\u00a00.20 vs 1.81\u00a0\u00b1\u00a00.08\u00a0mGy, respectively;\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u00a00.0001). The correlation rate was higher with the breath\u2010holding protocol (right lung field, 41.7\u00a0\u00b1\u00a09.3%; left lung field, 44.2\u00a0\u00b1\u00a08.9% vs right lung field, 33.4\u00a0\u00b1\u00a06.6%; left lung field, 36.0\u00a0\u00b1\u00a07.1%, respectively; both lung fields,\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u00a00.0001). In the lower lung fields, the correlation rate was markedly different (right, 15.3% difference; left, 14.1% difference; both lung fields,\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u00a00.0001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The breath\u2010holding protocol resulted in high imaging success rate among patients with respiratory diseases, yielding vivid images of pulmonary perfusion.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/acm2.13071","type":"journal-article","created":{"date-parts":[[2020,10,26]],"date-time":"2020-10-26T12:53:10Z","timestamp":1603716790000},"page":"247-255","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Pulmonary perfusion by chest digital dynamic radiography: Comparison between breath\u2010holding and deep\u2010breathing acquisition"],"prefix":"10.1002","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3948-1601","authenticated-orcid":false,"given":"Shota","family":"Yamamoto","sequence":"first","affiliation":[{"name":"Department of Radiology Tokai University Hachioji Hospital Tokai University School of Medicine Hachioji Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Terumitsu","family":"Hasebe","sequence":"additional","affiliation":[{"name":"Department of Radiology Tokai University Hachioji Hospital Tokai University School of Medicine Hachioji Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kosuke","family":"Tomita","sequence":"additional","affiliation":[{"name":"Department of Radiology Tokai University Hachioji Hospital Tokai University School of Medicine Hachioji Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shunsuke","family":"Kamei","sequence":"additional","affiliation":[{"name":"Department of Radiology Tokai University Hachioji Hospital Tokai University School of Medicine Hachioji Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomohiro","family":"Matsumoto","sequence":"additional","affiliation":[{"name":"Department of Radiology Tokai University Hachioji Hospital Tokai University School of Medicine Hachioji Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yutaka","family":"Imai","sequence":"additional","affiliation":[{"name":"Department of Radiology Tokai University Hachioji Hospital Tokai University School of Medicine Hachioji Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Genki","family":"Takahashi","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Tokai University Hachioji Hospital Tokai University School of Medicine Hachioji Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusuke","family":"Kondo","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Tokai University Hachioji Hospital Tokai University School of Medicine Hachioji Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoko","family":"Ito","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Tokai University Hachioji Hospital Tokai University School of Medicine Hachioji Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6044-6501","authenticated-orcid":false,"given":"Fumio","family":"Sakamaki","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Tokai University Hachioji Hospital Tokai University School of Medicine Hachioji Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,10,26]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1960.15.3.405"},{"key":"e_1_2_10_3_1","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1007\/s11936-018-0671-6","article-title":"State\u2010of\u2010the\u2010art imaging for the evaluation of pulmonary embolism","volume":"20","author":"Roshkovan L","year":"2018","journal-title":"Curr Treat Options Cardiovasc Med"},{"key":"e_1_2_10_4_1","first-page":"328","article-title":"Imaging lung perfusion","volume":"2012","author":"Hopkins SR","year":"1985","journal-title":"J Appl 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In: Radiological Protection for Medical Exposure to Ionizing Radiation. Safety Guide. IAEA Safety Standards Series No. SSG\u201046. Vienna: International atomic energy agency (IAEA);2018."},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.acra.2018.12.012"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehaa143"},{"key":"e_1_2_10_17_1","first-page":"ehaa443","article-title":"Pulmonary ventilation\u2010perfusion mismatch demonstrated by dynamic chest radiography in giant cell arteritis","author":"Yamasaki Y","year":"2020","journal-title":"Eur Heart J"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0899-7071(00)00245-X"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1590\/S1806-37562015000000266"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00408-014-9594-5"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.acra.2016.11.014"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2016.12.014"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1962.17.6.893"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/0034-5687(68)90007-8"}],"container-title":["Journal of Applied Clinical Medical Physics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/acm2.13071","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/acm2.13071","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aapm.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/acm2.13071","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,4]],"date-time":"2023-09-04T21:44:12Z","timestamp":1693863852000},"score":1,"resource":{"primary":{"URL":"https:\/\/aapm.onlinelibrary.wiley.com\/doi\/10.1002\/acm2.13071"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10,26]]},"references-count":23,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2020,11]]}},"alternative-id":["10.1002\/acm2.13071"],"URL":"https:\/\/doi.org\/10.1002\/acm2.13071","archive":["Portico"],"relation":{},"ISSN":["1526-9914","1526-9914"],"issn-type":[{"value":"1526-9914","type":"print"},{"value":"1526-9914","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,10,26]]},"assertion":[{"value":"2020-07-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-09-29","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-10-26","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}