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Before implantation, all the patients received MR scans to assess the lesion scope, extent, and nature. <jats:sup>125<\/jats:sup>I implantation target regions were based on the pre\u2010operative imaging. <jats:sup>125<\/jats:sup>I seeds were delivered to target regions via puncture needles under the real\u2010time guidance of MR. Computed tomography (CT)or MR was performed immediately after implantation and again every 3\u00a0months later.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>After successful <jats:sup>125<\/jats:sup>I implantation, all patients were also examined regularly to detect tumor recurrence, lymphatic, and distant metastases. To date, CT or MR verification showed that 13\/127 patients experienced tumor recurrence or lymphatic metastasis or distant metastasis. No seeds migration was observed, no serious treatment\u2010related complications affected patient quality of life, and no important organ (such as major cervical vessels, spinal cord, etc.) injuries were observed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Our results show that MR\u2010guided <jats:sup>125<\/jats:sup>I implantation is an effective approach to site\u2010specific treatment for oral and maxillofacial tumor, which could potentially reduce postoperative complications and tumor recurrence rates, increase patient survival, and improve quality of life.<\/jats:p><\/jats:sec>","DOI":"10.1002\/acm2.13112","type":"journal-article","created":{"date-parts":[[2020,12,10]],"date-time":"2020-12-10T09:53:45Z","timestamp":1607594025000},"page":"92-99","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["MR\u2010guided 125I seed implantation treatment for maxillofacial malignant 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