{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T14:57:35Z","timestamp":1772117855186,"version":"3.50.1"},"reference-count":21,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2021,3,29]],"date-time":"2021-03-29T00:00:00Z","timestamp":1616976000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["aapm.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Applied Clin Med Phys"],"published-print":{"date-parts":[[2021,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>This study examined the variation in the thyroid volume determined by the ellipsoid approximation method due to differences in the measured length or area of the cross\u2010sectional plane of CT images.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Forty\u2010five patients with Graves' disease were included in this retrospective study. We designated the three\u2010dimensional thyroid volumes extracted manually (\n                      <jats:italic>V<\/jats:italic>\n                      <jats:sub>CT<\/jats:sub>\n                      ) as the reference data and calculated five approximate volumes for comparison: (a) the mean volume of 8100 different thyroid volumes depending on the diameter of the cross\u2010sectional plane at the midpoint of the major axis, (\n                      <jats:italic>V<\/jats:italic>\n                      <jats:sub>ellipsoid,mean<\/jats:sub>\n                      ); (b) the volume using the maximum diameter and its orthogonal diameter, (\n                      <jats:italic>V<\/jats:italic>\n                      <jats:sub>ellipsoid,maxlength<\/jats:sub>\n                      ); (c) the maximum (\n                      <jats:italic>V<\/jats:italic>\n                      <jats:sub>ellipsoid,maxvolume<\/jats:sub>\n                      ); (d) minimum (\n                      <jats:italic>V<\/jats:italic>\n                      <jats:sub>ellipsoid,minvolume<\/jats:sub>\n                      ) of the 8100 thyroid volumes; and (e) the volume determined with an equivalent circle diameter, (\n                      <jats:italic>V<\/jats:italic>\n                      <jats:sub>ellipsoid,Heywood<\/jats:sub>\n                      ).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Thyroid volumes obtained via the ellipsoid approximation method varied depending on the diameter of the cross\u2010sectional plane and included a mean error of approximately 20%, while the concordance correlation coefficient (CCC) differed for each approximate volume. Among these volumes,\n                      <jats:italic>V<\/jats:italic>\n                      <jats:sub>ellipsoid,mean<\/jats:sub>\n                      and\n                      <jats:italic>V<\/jats:italic>\n                      <jats:sub>ellipsoid,Heywood<\/jats:sub>\n                      were in good agreement with\n                      <jats:italic>V<\/jats:italic>\n                      <jats:sub>CT<\/jats:sub>\n                      , according to single regression analyses and the resultant CCC values, with mean errors of 0.1% and 10.4%, respectively.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      While\n                      <jats:italic>V<\/jats:italic>\n                      <jats:sub>ellipsoid,Heywood<\/jats:sub>\n                      approximated thyroid volumes with vastly reduced errors, we recommend utilizing three\u2010dimensional thyroid volumetry if measurement accuracy is required.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/acm2.13125","type":"journal-article","created":{"date-parts":[[2021,3,29]],"date-time":"2021-03-29T04:17:37Z","timestamp":1616991457000},"page":"15-25","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Variation in thyroid volumes due to differences in the measured length or area of the cross\u2010sectional plane: A validation study of the ellipsoid approximation method using CT images"],"prefix":"10.1002","volume":"22","author":[{"given":"Naotoshi","family":"Fujita","sequence":"first","affiliation":[{"name":"Department of Radiological Technology Nagoya University Hospital Nagoya Japan"},{"name":"Department of Radiological and Medical Laboratory Sciences Nagoya University Graduate School of Medicine Nagoya Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katsuhiko","family":"Kato","sequence":"additional","affiliation":[{"name":"Functional Medical Imaging Biomedical Imaging Sciences Division of Advanced Information Health Sciences Department of Integrated Health Sciences Nagoya University Graduate School of Medicine Nagoya Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinji","family":"Abe","sequence":"additional","affiliation":[{"name":"Department of Radiological Technology Nagoya University Hospital Nagoya Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinji","family":"Naganawa","sequence":"additional","affiliation":[{"name":"Department of Radiology Nagoya University Graduate School of Medicine Nagoya Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,3,29]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1510030"},{"key":"e_1_2_9_3_1","first-page":"260","article-title":"Dosage determination with radioactive isotopes; practical considerations in therapy and protection","volume":"59","author":"Marinelli LD","year":"1948","journal-title":"Am J Roentgenol Radium Ther"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00259-010-1536-8"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00259-013-2387-x"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1148\/61.1.88"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1148\/58.1.68"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.7863\/jum.2008.27.12.1727"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s003300050138"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2009.07.030"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.13.12206"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1089\/105072501750302877"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1088\/0031-9155\/55\/21\/N02"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/jctb.5000560702"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.2307\/2532051"},{"key":"e_1_2_9_16_1","unstructured":"McBrideGB.A proposal for strength\u2010of\u2010agreement criteria for Lins Concordance Correlation Coefficient. 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