{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T12:56:27Z","timestamp":1774356987210,"version":"3.50.1"},"reference-count":29,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2022,2,14]],"date-time":"2022-02-14T00:00:00Z","timestamp":1644796800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["aapm.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Applied Clin Med Phys"],"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A multileaf collimator (MLC), virtual\u2010cone treatment technique has been commissioned for trigeminal neuralgia (TGN) at Tri\u2010Cities Cancer Center (TCCC). This novel technique was initially developed at the University of Alabama in Birmingham (UAB); it is designed to produce a spherical dose profile similar to a fixed, 5\u2010mm conical collimator distribution. Treatment is delivered with a 10\u2010MV flattening\u2010filter\u2010free (FFF) beam using a high\u2010definition MLC on a Varian Edge linear accelerator. Absolute dose output and profile measurements were performed in a 20 \u00d7 20 \u00d7 14 cm<jats:sup>3<\/jats:sup> solid\u2010water phantom using an Exradin W2 scintillation detector and Gafchromic EBT3 film. Dose output constancy for the virtual cone was evaluated over 6\u00a0months using an Exradin A11 parallel plate chamber. The photo\u2010neutron dose generated by these treatments was assessed at distances of 50 and 100 cm from isocenter using a Ludlum Model 30\u20137 Series Neutron Meter. TGN treatments at TCCC have been previously delivered at 6\u2010MV FFF using a 5\u2010mm stereotactic cone. To assess the dosimetric impact of using a virtual cone, eight patients previously treated for TGN with a 5\u2010mm cone were re\u2010planned using a virtual cone. Seven patients have now been treated for TGN using a virtual cone at TCCC. Patient\u2010specific quality assurance was performed for each patient using Gafchromic EBT\u2010XD film inside a Standard Imaging Stereotactic Dose Verification Phantom. The commissioning results demonstrate that the virtual\u2010cone dosimetry, first described at UAB, is reproducible on a second Edge linear accelerator at an independent clinical site. The virtual cone is a credible alternative to a physical, stereotactic cone for the treatment of TGN at TCCC.<\/jats:p>","DOI":"10.1002\/acm2.13562","type":"journal-article","created":{"date-parts":[[2022,2,14]],"date-time":"2022-02-14T15:14:24Z","timestamp":1644851664000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Commissioning a multileaf collimator virtual cone for the stereotactic radiosurgery of trigeminal neuralgia"],"prefix":"10.1002","volume":"23","author":[{"given":"Thomas A. 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