{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T18:40:52Z","timestamp":1789929652050,"version":"4.0.1"},"reference-count":27,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2023,5,29]],"date-time":"2023-05-29T00:00:00Z","timestamp":1685318400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100021171","name":"Basic and Applied Basic Research Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2021A1515220140"],"award-info":[{"award-number":["2021A1515220140"]}],"id":[{"id":"10.13039\/501100021171","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["aapm.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Applied Clin Med Phys"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>To investigate the difference of the fluence map optimization (FMO) and Stochastic platform optimization (SPO) algorithm in a newly\u2010introduced treatment planning system (TPS). Methods: 34 cervical cancer patients with definitive radiation were retrospectively analyzed. Each patient has four plans: FMO with fixed jaw plans (FMO\u2010FJ) and no fixed jaw plans (FMO\u2010NFJ); SPO with fixed jaw plans (SPO\u2010FJ) and no fixed jaw plans (SPO\u2010NFJ). Dosimetric parameters, Modulation Complexity Score (MCS), Gamma Pass Rate (GPR) and delivery time were analyzed among the four plans. Results: For target coverage, SPO\u2010FJ plans are the best ones (<jats:italic>P<\/jats:italic>\u00a0\u2264\u00a00.00). FMO plans are better than SPO\u2010NFJ plans (<jats:italic>P<\/jats:italic>\u00a0\u2264\u00a00.00). For OARs sparing, SPO\u2010FJ plans are better than FMO plans for mostly OARs (<jats:italic>P<\/jats:italic>\u00a0\u2264\u00a00.04). Additionally, SPO\u2010FJ plans are better than SPO\u2010NFJ plans (<jats:italic>P<\/jats:italic>\u00a0\u2264\u00a00.02), except for rectum V45Gy. Compared to SPO\u2010NFJ plans, the FMO plans delivered less dose to bladder, rectum, colon V40Gy and pelvic bone V40Gy\u00a0(<jats:italic>P<\/jats:italic>\u00a0\u2264\u00a00.04). Meanwhile, the SPO\u2010NFJ plans showed superiority in MU, delivery time, MCS and GPR in all plans. In terms of delivery time and MCS, the SPO\u2010FJ plans are better than FMO plans. FMO\u2010FJ plans are better than FMO\u2010NFJ plans in delivery efficiency. MCSs are strongly correlated with PCTV length, which are negatively with PCTV length (<jats:italic>P<\/jats:italic>\u00a0\u2264\u00a00.03). The delivery time and MUs of the four plans are strongly correlated (<jats:italic>P<\/jats:italic>\u00a0\u2264\u00a00.02). Comparing plans with fixed or no fixed jaw in two algorithms, no difference was found in FMO plans in target coverage and minor difference in Kidney_L Dmean, Mu and delivery time between PCTV width\u226415.5\u00a0cm group and\u00a0&gt;15.5\u00a0cm group. For SPO plans, SPO\u2010FJ plans showed more superiority in target coverage and OARs sparing than the SPO\u2010NFJ plans in the two groups. Conclusions: SPO\u2010FJ plans showed superiority in target coverage and OARs sparing, as well as higher delivery efficiency in the four plans.<\/jats:p>","DOI":"10.1002\/acm2.14050","type":"journal-article","created":{"date-parts":[[2023,5,30]],"date-time":"2023-05-30T05:41:09Z","timestamp":1685425269000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Plan quality and treatment efficiency assurance of two VMAT optimization for cervical cancer radiotherapy"],"prefix":"10.1002","volume":"24","author":[{"given":"Sijuan","family":"Huang","sequence":"first","affiliation":[{"name":"Department of Radiation Oncology, Sun Yat\u2010sen University Cancer Center State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy  Guangzhou Guangdong 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Oncology, Sun Yat\u2010sen University Cancer Center State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy  Guangzhou Guangdong China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinhan","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Sun Yat\u2010sen University Cancer Center State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy  Guangzhou Guangdong China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinlong","family":"Du","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Sun Yat\u2010sen University Cancer Center State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine Guangdong Key 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