{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T23:26:06Z","timestamp":1792106766065,"version":"4.4.0"},"reference-count":39,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,11,29]],"date-time":"2024-11-29T00:00:00Z","timestamp":1732838400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["aapm.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Applied Clin Med Phys"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>The objective of this study is to evaluate the impact of different belly board and daily changes in patient's body\u2010mass factor (BMF) on setup displacement in radiotherapy for rectal cancer.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Twenty\u2010five patients were immobilized using the thermoplastic mask with belly board (TM\u2010BB), and 30 used the vacuum bag cushion with belly board (VBC\u2010BB), performing daily cone\u2010beam computed tomography (CBCT) scans 625 times and 750 times, respectively. Daily pretreatment CBCT scans were registered to the planned CT images for BMF change determination and setup displacement measurement. Independent t\u2010tests compared setup displacement between the two groups in left\u2010right (LR), superior\u2010inferior (SI), and anterior\u2010posterior (AP) directions, as well as the BMF changes. The impact of daily BMF changes on setup displacement was evaluated using multivariate logistic regression and 10\u2010fold cross\u2010validation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The setup displacement for TM\u2010BB in the LR, SI, and AP directions were 0.31\u00a0\u00b1\u00a00.25, 0.58\u00a0\u00b1\u00a00.40, and 0.19\u00a0\u00b1\u00a00.18\u00a0cm, respectively, while VBC\u2010BB showed 0.19\u00a0\u00b1\u00a00.15, 0.26\u00a0\u00b1\u00a00.22, and 0.36\u00a0\u00b1\u00a00.29\u00a0cm in the corresponding directions, respectively. Margins of planning target volume (PTV) for TM\u2010BB were 8, 10, and 6\u00a0mm in LR, SI, and AP directions, while VBC\u2010BB showed margins of 5,7, and 8\u00a0mm, respectively. The daily BMF changes for both groups were ranked in descending order as follows: sacral rotation angle (RS), hip lateral diameter (HLD), and hip anterior\u2010posterior diameter (HAPD). HAPD was the main factor affecting setup displacement in both the AP and SI directions in TM\u2010BB, while RS was the primary factor for setup displacement in the AP direction in VBC\u2010BB.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Compared with TM\u2010BB, VBC\u2010BB had a larger AP displacement but smaller in LR and SI displacement. Daily changes in BMF have distinct effects on setup displacement in different immobilization devices. Image\u2010guided radiation therapy (IGRT) is highly recommended and BMF changes should be given consideration during radiotherapy.<\/jats:p><\/jats:sec>","DOI":"10.1002\/acm2.14573","type":"journal-article","created":{"date-parts":[[2024,11,29]],"date-time":"2024-11-29T14:34:31Z","timestamp":1732890871000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Impact of belly board immobilization devices and body mass factor on setup displacement using daily cone\u2010beam CT in rectal cancer radiotherapy"],"prefix":"10.1002","volume":"26","author":[{"given":"Junjie","family":"Ruan","sequence":"first","affiliation":[{"name":"State Key Laboratory of Oncology in South China Guangdong Provincial Clinical Research Center for Cancer Sun Yat\u2010sen University Cancer Center  Guangzhou P. R. 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