{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T02:05:30Z","timestamp":1784167530473,"version":"3.55.0"},"reference-count":40,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2025,8,21]],"date-time":"2025-08-21T00:00:00Z","timestamp":1755734400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,8,21]],"date-time":"2025-08-21T00:00:00Z","timestamp":1755734400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["aapm.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Applied Clin Med Phys"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>The deep inspiration breath\u2010hold (DIBH) technique,\u00a0a method\u00a0used to\u00a0minimize\u00a0radiation exposure to normal tissues in breast cancer patients,\u00a0has primarily been\u00a0applied to patients with left breast cancer.\u00a0However, this\u00a0study,\u00a0with its unique focus on right breast cancer, aims\u00a0to evaluate the\u00a0potential benefits\u00a0of DIBH on the right coronary artery (RCA), cardiac substructures, and liver dose in right breast cancer radiotherapy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>Forty right\u2010sided breast cancer patients were included in this study. Radiotherapy planning using 3D, IMRT, and VMAT was performed using both free\u2010breathing (FB) and DIBH techniques. Two treatment plans were generated per patient, and organ\u2010at\u2010risk (OAR) doses were compared using the Wilcoxon signed\u2010rank test. Patients were analyzed based on regional nodal irradiation (RNI) status.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The mean radiation doses (Dmean) to the liver, ipsilateral lung, heart, and RCA region were 5.4, 15.9, 2.5, and 6\u00a0Gy with FB, decreasing to 4.6, 12.6, 1.6, and 3.6\u00a0Gy with DIBH. For the left ventricle, right ventricle, left atrium, and right atrium, the Dmean values were 1.2, 2.2, 2, and 4.6\u00a0Gy with FB, versus 0.76, 1.8\u00a0Gy, 1.2, and 3.2\u00a0Gy with DIBH. DIBH significantly reduced liver and lung doses in all patients, while heart and RCA doses reductions were observed only in those receiving RNI.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The use of the DIBH technique can significantly reduce radiation exposure to OARs\u00a0in right\u2010sided breast cancer radiotherapy. Despite a slight increase in treatment duration, DIBH should be considered for right breast cancer radiotherapy to minimize radiation\u2010related toxicity.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/acm2.70216","type":"journal-article","created":{"date-parts":[[2025,8,22]],"date-time":"2025-08-22T01:50:05Z","timestamp":1755827405000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Comprehensive analysis of the role of deep inspiration breath\u2010hold in right\u2010sided breast cancer radiotherapy: A focus on cardiac substructures and right coronary artery"],"prefix":"10.1002","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0283-1599","authenticated-orcid":false,"given":"Volkan","family":"Semiz","sequence":"first","affiliation":[{"name":"Department of Radiation Oncology Dokuz Eylul University Faculty of Medicine  Izmir Turkey"},{"name":"Department of Radiation Oncology Izmir City 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