{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T20:31:20Z","timestamp":1792182680848,"version":"4.4.0"},"reference-count":30,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T00:00:00Z","timestamp":1756425600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T00:00:00Z","timestamp":1756425600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82403993"],"award-info":[{"award-number":["82403993"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["aapm.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Applied Clin Med Phys"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>This study aimed to comprehensively compare the dosimetric characteristics of three different radiotherapy techniques\u2014hybrid intensity\u2010modulated radiotherapy (hy\u2010IMRT), tangential volumetric\u2010modulated arc therapy (t\u2010VMAT), and continuous volumetric\u2010modulated arc therapy (c\u2010VMAT)\u2014used after breast\u2010conserving surgery for left\u2010sided breast cancer in the target area and organs at risk (OARs) after breast\u2010conserving surgery for left\u2010sided breast cancer. This evaluation aims to provide a solid basis for individualized radiotherapy planning in clinical practice.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Twenty female patients who underwent breast\u2014conserving surgery for left\u2014sided breast cancer were retrospectively selected. These patients were treated with hy\u2010IMRT, t\u2010VMAT, or c\u2010VMAT. The doses received by the target area and OARs were precisely evaluated. Additionally, the dose distribution in normal tissues and treatment time of the three radiotherapy plans were carefully compared.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      All three techniques could meet the target zone dose requirements. In the planning gross tumor volume (PGTV), the average dose of hy\u2010IMRT was the highest. c\u2010VMAT demonstrated the best homogeneity index (HI) and conformity index (CI). For the planning target volume (PTV), c\u2010VMAT also showed outstanding performance in terms of homogeneity and conformity (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.001). Regarding OAR doses, although there was no significant difference in the mean cardiac dose among the three techniques (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.69), c\u2010VMAT had lower values in cardiac V10 dose volume, mean coronary left anterior descending (LAD) artery dose, and V20, V30, and V40 dose volumes, irradiating less of the cardiac low\u2014dose and high\u2014dose regions. c\u2010VMAT had lower left lung V30 and V40 doses, but its mean dose to the right lung was significantly higher than that of the other two groups. In terms of treatment time, t\u2010VMAT was significantly shorter than the other two groups, indicating the highest efficiency (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>C\u2010VMAT exhibits obvious advantages in target area uniformity, conformality, and protection of the heart and the affected lung. However, its significant dose impact on the right lung cannot be ignored and requires further attention. On the other hand, t\u2010VMAT has a remarkable advantage in treatment time. This study offers valuable references for clinicians to select the most suitable radiotherapy technique according to patients' specific conditions, such as tumor location, size, and OAR anatomical structures, aiming to optimize treatment outcomes and minimize adverse effects.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/acm2.70257","type":"journal-article","created":{"date-parts":[[2025,8,30]],"date-time":"2025-08-30T01:34:22Z","timestamp":1756517662000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Dosimetric comparison of hybrid IMRT and different arc techniques VMAT after breast\u2010conserving surgery for left\u2010sided breast cancer"],"prefix":"10.1002","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2188-6360","authenticated-orcid":false,"given":"Xin","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Radiation Oncology the First Affiliated Hospital of 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