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We evaluated a 38\u2010year\u2010old man with memory complaints, common symptoms in adult polyglucosan body disease subtype, and investigated cognitive and functional <jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content> changes associated with two 25\u2010sessions of adaptive working memory training. He showed improved trained and nontrained working memory up to 6\u2010months after the training sessions. On functional <jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content>, he showed increased cortical activation 1\u20133 months after training, but both increased and decreased activation 6\u2010months later. Working memory training appears to be beneficial to patients with adult polyglucosan body disease, although continued training may be required to maintain improvements.<\/jats:p>","DOI":"10.1002\/acn3.394","type":"journal-article","created":{"date-parts":[[2017,2,23]],"date-time":"2017-02-23T21:44:33Z","timestamp":1487886273000},"page":"217-222","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Neural correlates of adaptive working memory training in a glycogen storage disease type\u2010<scp>IV<\/scp> patient"],"prefix":"10.1002","volume":"4","author":[{"given":"Kristin","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Medicine University of Hawai'i at M\u0101noa  Honolulu Hawaii"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Ernst","sequence":"additional","affiliation":[{"name":"Department of Medicine University of Hawai'i at M\u0101noa  Honolulu Hawaii"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gro","family":"L\u00f8haugen","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine Childrens and Women's Health Norwegian University of Science and Technology  Trondheim Norway"},{"name":"Department of Pediatrics S\u00f8rlandet Hospital  Arendal Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xin","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Medicine University of Hawai'i at M\u0101noa  Honolulu Hawaii"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linda","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Medicine University of Hawai'i at M\u0101noa  Honolulu Hawaii"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,2,23]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI118517"},{"key":"e_1_2_8_3_1","first-page":"1993","volume-title":"GeneReviews","author":"Magoulas P","year":"1993"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.2174\/1566524024605815"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01799348"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.23598"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00867422"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1994.00540130124021"},{"key":"e_1_2_8_9_1","volume-title":"Wechsler adult intelligence scale\u2010fourth edition administration and scoring manual","author":"Wechsler D","year":"2008"},{"key":"e_1_2_8_10_1","volume-title":"A compendium of neuropsychological tests administration, norms, and commentary","author":"Strauss E","year":"2006"},{"key":"e_1_2_8_11_1","volume-title":"Delis\u2010Kaplan executive function system examiner's manual (D\u2010KEFS\u2122)","author":"Delis DC","year":"2001"},{"key":"e_1_2_8_12_1","volume-title":"Wechsler Adult Intelligence Scale\u00ae \u2010 Third Edition (WAIS\u00ae\u2010III)","author":"Wechsler D","year":"1997"},{"key":"e_1_2_8_13_1","unstructured":"Manual. 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