{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T04:06:57Z","timestamp":1769573217427,"version":"3.49.0"},"reference-count":39,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2019,7,15]],"date-time":"2019-07-15T00:00:00Z","timestamp":1563148800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100005795","name":"Chang Gung Memorial Hospital, Linkou","doi-asserted-by":"publisher","award":["201800769B0"],"award-info":[{"award-number":["201800769B0"]}],"id":[{"id":"10.13039\/501100005795","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ann Clin Transl Neurol"],"published-print":{"date-parts":[[2019,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>This study aims to investigate the etiology and prognosis of spinal cord infarction (SCI).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Over a period of 16\u00a0years, we retrospectively analyzed 31 patients with SCI. Demographic features and symptom presentations were carefully documented. Etiology\u2010specific MRI features, such as the length and distribution of the lesions and owl\u2019s eyes sign, were recorded and analyzed to determine their associations with the clinical signs\/symptoms.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In total, seven patients had aortic or vertebral artery dissections. We divided the patients with SCI into two groups: those with or without vessel dissection. Among SCI patients, the onset age was younger, and the proportion of patients with long\u2010segment lesions and posterior pattern involvement on axial view was higher in the group with dissection than in the group without dissection (all <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.05). The lesions were frequently located in the upper cervical or lower thoracic\u2010lumbar regions, and the lengths of the lesions were associated with 1\u2010month outcomes, suggesting that artery dissection may contribute to the longitudinal and posterior extension of SCI. In contrast, among patients without dissection, the range of longitudinal extensions of in spans of vertebral bodies was broader (range, 1\u20138). A higher proportion of patients had focal pain adjacent to the lesion (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.05) and a poorer 1\u2010month outcome (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.04) in the long\u2010segment lesion group than in the short\u2010segment lesion group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>A detailed history and the use of modern imaging tools may help clinicians search for vessel dissection and other etiologies, evaluate the spatial extension of lesions in SCI, and predict prognosis.<\/jats:p><\/jats:sec>","DOI":"10.1002\/acn3.50840","type":"journal-article","created":{"date-parts":[[2019,7,15]],"date-time":"2019-07-15T07:04:20Z","timestamp":1563174260000},"page":"1456-1464","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["The etiologies and prognosis associated with spinal cord infarction"],"prefix":"10.1002","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6422-8870","authenticated-orcid":false,"given":"Jung Lung","family":"Hsu","sequence":"first","affiliation":[{"name":"Department of Neurology Linkou Medical Center, Chang Gung Memorial Hospital and College of Medicine, Chang Gung University Taoyuan Taiwan"},{"name":"Graduate Institute of Mind, Brain, and Consciousness Taipei Medical University Taipei Taiwan"},{"name":"Brain and Consciousness Research Center TMU Shuang Ho Hospital New Taipei City Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mei\u2010Yun","family":"Cheng","sequence":"additional","affiliation":[{"name":"Department of Neurology Linkou Medical Center, Chang Gung Memorial Hospital and College of Medicine, Chang Gung University Taoyuan Taiwan"},{"name":"Institute of Molecular Medicine National Tsing Hua University Hsinchu Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ming\u2010Feng","family":"Liao","sequence":"additional","affiliation":[{"name":"Department of Neurology Linkou Medical Center, Chang Gung Memorial Hospital and College of Medicine, Chang Gung University Taoyuan Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hui\u2010Ching","family":"Hsu","sequence":"additional","affiliation":[{"name":"Department of Traditional Chinese Medicine, Division of Chinese Acupuncture and Traumatology Chang Gung Memorial Hospital, Linkou Medical Center and Chang Gung University College of Medicine Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi\u2010Ching","family":"Weng","sequence":"additional","affiliation":[{"name":"Department of Neurology Linkou Medical Center, Chang Gung Memorial Hospital and College of Medicine, Chang Gung University Taoyuan Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kuo\u2010Hsuan","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Neurology Linkou Medical Center, Chang Gung Memorial Hospital and College of Medicine, Chang Gung University Taoyuan Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hong\u2010Shiu","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Neurology Linkou Medical Center, Chang Gung Memorial Hospital and College of Medicine, Chang Gung University Taoyuan Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hung\u2010Chou","family":"Kuo","sequence":"additional","affiliation":[{"name":"Department of Neurology Linkou Medical Center, Chang Gung Memorial Hospital and College of Medicine, Chang Gung University Taoyuan 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