{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T19:41:59Z","timestamp":1782934919916,"version":"3.54.5"},"reference-count":10,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2019,9,17]],"date-time":"2019-09-17T00:00:00Z","timestamp":1568678400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ann Clin Transl Neurol"],"published-print":{"date-parts":[[2019,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Neuromyelitis optica is an immune\u2010mediated disease characterized by a relapsing course, resulting in progressive disability. In children, given the long life expectancy, a disease\u2010modifying treatment could be particularly desirable. Unfortunately, the currently available treatment strategies with this potential are scarce. Very limited data are available about the use of allogeneic hematopoietic stem cell transplantation (HSCT) for autoimmune neurological diseases. In this report, we present a pediatric case successfully treated with allogeneic HSCT from an HLA\u2010haploidentical donor, after ex vivo TCR\/CD19\u2010depletion of the graft. To the best of our knowledge, this is the first case of a pediatric patient to benefit from such a treatment.<\/jats:p>","DOI":"10.1002\/acn3.50843","type":"journal-article","created":{"date-parts":[[2019,9,17]],"date-time":"2019-09-17T11:15:28Z","timestamp":1568718928000},"page":"2110-2113","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["T\u2010cell depleted HLA\u2010haploidentical HSCT in a child with neuromyelitis optica"],"prefix":"10.1002","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4127-6914","authenticated-orcid":false,"given":"Giulia","family":"Ceglie","sequence":"first","affiliation":[{"name":"Department of Onco-Hematology and Cell and Gene Therapy Bambino Ges\u00f9 Children's Hospital (IRCCS) Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Papetti","sequence":"additional","affiliation":[{"name":"Department of Neuroscience Pediatric Multiple 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