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The Outcome Measures for Myotonic Dystrophy (OMMYD) group proposed a battery of functional outcomes: 6\u2010minute walk test, 30\u00a0seconds sit and stand test, timed 10\u00a0m walk test, timed 10\u00a0m walk\/run test, and nine\u2010hole peg test. This, however, required a large\u2010scale investigation,<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A cohort of 213 patients enrolled in the natural history study, PhenoDM1, was analyzed in cross\u2010sectional analysis and subsequently 98 patients were followed for longitudinal analysis. We aimed to assess: (1) feasibility and best practice; (2) intra\u2010session reliability; (3) validity; and (4) behavior over time, of these tests.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>OMMYD outcomes proved feasible as 96% of the participants completed at least one trial for all tests and more than half (<jats:italic>n<\/jats:italic>\u00a0=\u00a0113) performed all three trials of each test. Body mass index and disease severity associate with functional capacity. There was a significant difference between the first and second trials of each test. There was a moderate to strong correlation between these functional outcomes and muscle strength, disease severity and patient\u2010reported outcomes. All outcomes after 1\u00a0year detected a change in functional capacity except the nine\u2010hole peg test.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>These tests can be used as a battery of outcomes or independently based on the shown overlapping psychometric features and strong cross\u2010correlations. Due to the large and heterogeneous sample of this study, these results can serve as reference values for future studies.<\/jats:p><\/jats:sec>","DOI":"10.1002\/acn3.50845","type":"journal-article","created":{"date-parts":[[2019,7,22]],"date-time":"2019-07-22T11:54:23Z","timestamp":1563796463000},"page":"1487-1497","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Analysis of the functional capacity outcome measures for myotonic dystrophy"],"prefix":"10.1002","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0488-9631","authenticated-orcid":false,"given":"Aura Cecilia","family":"Jimenez\u2010Moreno","sequence":"first","affiliation":[{"name":"John Walton Muscular Dystrophy Research Centre, Institute of Genetic Medicine Newcastle University Newcastle upon Tyne UK"},{"name":"Welcome Trust Mitochondrial Research Centre, Institute of Neurosciences Newcastle University Newcastle upon Tyne 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