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Which lessons can we learn? We identified relevant publications (until 26 July 2020) using systematic searches in PubMed, Web of Science, and Ovid EMBASE with predefined search strings. A total of 4571 unique publications were retrieved, out of which 378 publications were selected for in\u2010depth analysis by two raters, including a total of 17549 (out of which were 14418 SARS\u2010CoV\u20102) patients. Neurological complications and associated neuroradiological manifestations are prevalent for all HCoVs (HCoV\u2010229E, HKU1, NL63, OC43, Middle East respiratory syndrome (MERS)\u2010CoV, SARS\u2010CoV\u20101, and SARS\u2010CoV\u20102). Moreover there are similarities in symptomatology across different HCoVs, particularly between SARS\u2010CoV\u20101 and SARS\u2010CoV\u20102. Common neurological manifestations include fatigue, headache, and smell\/taste disorders. Additionally, clinicians need to be attentive for at least five classes of neurological complications: (1) Cerebrovascular disorders including ischemic stroke and macro\/micro\u2010hemorrhages, (2) encephalopathies, (3) para\u2010\/postinfectious immune\u2010mediated complications such as Guillain\u2010Barr\u00e9 syndrome and acute disseminated encephalomyelitis, (4) (meningo\u2010)encephalitis, potentially with concomitant seizures, and (5) neuropsychiatric complications such as psychosis and mood disorders. Our systematic review highlights the need for vigilance regarding neurological complications in patients infected by SARS\u2010CoV\u20102 and other HCoVs, especially since some complications may result in chronic disability. Neuroimaging protocols should be designed to specifically screen for these complications. Therefore, we propose practical imaging guidelines to facilitate the diagnostic workup and monitoring of patients infected with HCoVs.<\/jats:p>","DOI":"10.1002\/acn3.51166","type":"journal-article","created":{"date-parts":[[2020,8,27]],"date-time":"2020-08-27T14:20:13Z","timestamp":1598538013000},"page":"2057-2071","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":70,"title":["Neurological manifestations of coronavirus infections \u2013 a systematic review"],"prefix":"10.1002","volume":"7","author":[{"given":"Jesper","family":"Almqvist","sequence":"first","affiliation":[{"name":"Department of Neuroradiology Karolinska University Hospital Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tobias","family":"Granberg","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology Karolinska University Hospital Stockholm Sweden"},{"name":"Department of Clinical Neuroscience Karolinska Institutet Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonios","family":"Tzortzakakis","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology Karolinska University Hospital Stockholm Sweden"},{"name":"Department for Clinical Science, Intervention and Technology Karolinska Institutet Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefanos","family":"Klironomos","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology Karolinska University Hospital Stockholm Sweden"},{"name":"Department of Clinical Neuroscience Karolinska Institutet Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evangelia","family":"Kollia","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology Karolinska University Hospital Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claes","family":"\u00d6hberg","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology Karolinska University Hospital Stockholm Sweden"},{"name":"Department of Clinical Neuroscience Karolinska Institutet Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roland","family":"Martin","sequence":"additional","affiliation":[{"name":"Neuroimmunology and MS Research Section Neurology Clinic University Zurich University Hospital Zurich Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fredrik","family":"Piehl","sequence":"additional","affiliation":[{"name":"Department of Clinical Neuroscience Karolinska Institutet Stockholm Sweden"},{"name":"Center of Neurology Academic Specialist Center Stockholm Health Services Stockholm Sweden"},{"name":"Center for Molecular Medicine Karolinska Institutet Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9217-1445","authenticated-orcid":false,"given":"Russell","family":"Ouellette","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology Karolinska University Hospital Stockholm Sweden"},{"name":"Department of Clinical Neuroscience Karolinska Institutet Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1362-4819","authenticated-orcid":false,"given":"Benjamin V.","family":"Ineichen","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology Karolinska University Hospital Stockholm Sweden"},{"name":"Department of Clinical Neuroscience Karolinska Institutet Stockholm Sweden"},{"name":"Neuroimmunology and MS Research Section Neurology Clinic University Zurich University Hospital Zurich Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,8,27]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa030781"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.onehlt.2016.12.001"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1128\/MMBR.69.4.635-664.2005"},{"key":"e_1_2_10_5_1","first-page":"85","volume-title":"Coronaviruses: a comparative review. 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