{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T14:33:54Z","timestamp":1762353234913,"version":"3.40.5"},"reference-count":15,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2022,8,27]],"date-time":"2022-08-27T00:00:00Z","timestamp":1661558400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ann Clin Transl Neurol"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>This retrospective case\u2013controlled study was performed to evaluate whether Epileptiform Activity, suspected clinical seizures, and\/or 2HELPS2B\/S after nontraumatic Intraparenchymal Hemorrhage or Subarachnoid Hemorrhage can predict Epilepsy. Hundred and thirty\u2010two patients were included\u201429 (Epilepsy), 103 (Control Group). After matching, the average effect for all three risk factors was significant as follows: (1) Epileptiform Activity (<jats:italic>p<\/jats:italic>\u2009=\u20090.012, odds ratio 3.14), (2) suspected seizures (<jats:italic>p<\/jats:italic>\u2009=\u20090.021, odds ratio 3.78), and (3) 2HELPS2B\/S score (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001, odds ratio 4.94). This study shows that Epileptiform Activity, suspected seizures, and particularly, the 2HELPS2B\/S score in the acute phase are risk factors for the development of epilepsy after nontraumatic intraparenchymal and subarachnoid hemorrhage.<\/jats:p>","DOI":"10.1002\/acn3.51637","type":"journal-article","created":{"date-parts":[[2022,8,28]],"date-time":"2022-08-28T06:48:38Z","timestamp":1661669318000},"page":"1475-1480","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Epileptiform activity predicts epileptogenesis in cerebral hemorrhage"],"prefix":"10.1002","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2890-6464","authenticated-orcid":false,"given":"Tseun Han James","family":"Kong","sequence":"first","affiliation":[{"name":"Department of Neurology University of Wisconsin\u2010Madison  Madison Wisconsin USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad","family":"Abdul Azeem","sequence":"additional","affiliation":[{"name":"Department of Neurology University of Wisconsin\u2010Madison  Madison Wisconsin USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayesha","family":"Naeem","sequence":"additional","affiliation":[{"name":"Department of Neurology University of Wisconsin\u2010Madison  Madison Wisconsin USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shawn","family":"Allen","sequence":"additional","affiliation":[{"name":"Department of Neurology University of Wisconsin\u2010Madison  Madison Wisconsin USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer Ahjin","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Neurology Yale University  New Haven Connecticut USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9103-1798","authenticated-orcid":false,"given":"Aaron F.","family":"Struck","sequence":"additional","affiliation":[{"name":"Department of Neurology University of Wisconsin\u2010Madison  Madison Wisconsin USA"},{"name":"William S. 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