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The primary outcome measure was postoperative myasthenic crisis (POMC). A predictive model was constructed using logistic regression and presented in a nomogram. The area under the receiver operating characteristic curve (AUC) was calculated to examine the performance. The study population was divided into high\u2010 and low\u2010risk groups according to Youden index. Calibration curves with 1000 replications bootstrap resampling were plotted to visualize the calibration of the nomogram. Decision curve analyses (DCA) with 1000 replications bootstrap resampling were performed to evaluate the clinical usefulness of the model.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 445 patients were enrolled. Five variables were screened including thymus imaging, onset age, MGFA classification, preoperative treatment regimen, and surgical approach. The model exhibited moderate discriminative ability with AUC value 0.771. The threshold probability was 0.113, which was used to differentiate between high\u2010 and low\u2010risk groups. The sensitivity and specificity were 72.1% and 77.1%, respectively. The high\u2010risk group had an 8.70\u2010fold higher risk of POMC. The calibration plot showed that when the probability was between 0 and 0.5, the deviation calibration curve of the model was consistent with the ideal curve.<\/jats:p><\/jats:sec><jats:sec><jats:title>Interpretation<\/jats:title><jats:p>This nomogram could assist in identifying patients at higher risk of POMC and determining the optimal surgical time for these patients.<\/jats:p><\/jats:sec>","DOI":"10.1002\/acn3.51752","type":"journal-article","created":{"date-parts":[[2023,3,7]],"date-time":"2023-03-07T05:12:04Z","timestamp":1678165924000},"page":"644-655","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Nomogram for predicting the risk of postoperative myasthenic crisis in patients with thymectomy"],"prefix":"10.1002","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8190-4022","authenticated-orcid":false,"given":"Zhe","family":"Ruan","sequence":"first","affiliation":[{"name":"Department of 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