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The most common initial phenotype is acute disseminated encephalomyelitis, especially among children younger than five years, followed by optic neuritis (ON) and\/or transverse myelitis. Approximately one\u2010quarter of children with MOGAD have at least one relapse that typically occurs within three years of disease onset and often includes ON, even if ON was not present at onset. Clinical risk factors for a relapsing course have not been elucidated.<\/jats:p>","DOI":"10.1002\/acn3.51759","type":"journal-article","created":{"date-parts":[[2023,3,31]],"date-time":"2023-03-31T18:11:01Z","timestamp":1680286261000},"page":"672-685","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":39,"title":["Attack phenotypes and disease course in pediatric <scp>MOGAD<\/scp>"],"prefix":"10.1002","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8350-8234","authenticated-orcid":false,"given":"Jonathan D.","family":"Santoro","sequence":"first","affiliation":[{"name":"Division of Neuroimmunology, Department of Pediatrics Children's Hospital Los Angeles  Los Angeles California USA"},{"name":"Department of Neurology Keck School of Medicine at the University of Southern California  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9463-6306","authenticated-orcid":false,"given":"Timothy","family":"Beukelman","sequence":"additional","affiliation":[{"name":"Epi Excellence LLC  Garnet Valley Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheryl","family":"Hemingway","sequence":"additional","affiliation":[{"name":"Great Ormond Street Hospital for Children  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suvi R. 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