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In this retrospective study, we analyzed a cohort of Parkinson's disease patients treated with dopamine agonists and investigated the influence of the dopamine D4 receptor gene polymorphism, DRD4 7R+, which is linked to psychiatric disorders, impulsive traits, and addictive behaviors. We found that DRD4 7R+ is a significant genetic risk factor associated with the severity of ICD.<\/jats:p>","DOI":"10.1002\/acn3.52111","type":"journal-article","created":{"date-parts":[[2024,7,2]],"date-time":"2024-07-02T01:56:07Z","timestamp":1719885367000},"page":"2222-2229","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["<scp>DRD4<\/scp>\n                    gene polymorphism and impulse control disorder induced by dopamine agonists in Parkinson's disease"],"prefix":"10.1002","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1795-0072","authenticated-orcid":false,"given":"Viviana","family":"Torres","sequence":"first","affiliation":[{"name":"Parkinson's Disease and Movement Disorders Unit, Neurology Service Institut de Neurociencies UBNeuro, Hospital Cl\u00ednic Universitari de Barcelona  Barcelona Catalonia 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