{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T22:17:59Z","timestamp":1784240279344,"version":"3.55.0"},"reference-count":46,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2024,10,11]],"date-time":"2024-10-11T00:00:00Z","timestamp":1728604800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100018537","name":"National Science and Technology Major Project","doi-asserted-by":"publisher","award":["2022ZD0118003"],"award-info":[{"award-number":["2022ZD0118003"]}],"id":[{"id":"10.13039\/501100018537","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82371302"],"award-info":[{"award-number":["82371302"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ann Clin Transl Neurol"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>The association between gait speed and adverse outcomes after stroke has not been fully illustrated. This study aimed to explore the association of gait speed on long\u2010term outcomes in minor stroke or transient ischemic attack (TIA).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We performed a longitudinal study with acute minor stroke or TIA based on a subgroup of the Third China National Stroke Registry data. The gait speed was evaluated using a 10\u2010meter walking test at discharge and 3\u2009months after the stroke onset. The primary outcomes were poor functional outcomes at 1\u2009year, defined by a modified Rankin Score (mRS) of 2\u20136. Additional outcomes included all\u2010cause death, ambulate dependency (mRS score 4\u20136), cognitive impairment (Montreal Cognitive Assessment &lt;26), stroke recurrence, and composite vascular events.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The study sample included a total of 1542 stroke patients with a median age of 60 (53\u201368). At 1\u2010year follow\u2010up, 140 (9.20%) patients experienced poor functional outcomes. Faster gait speed at discharge was associated with lower incidence of poor functional outcome (OR\u2009=\u20090.89; 95% CI, 0.84\u20130.94), cognitive impairment (OR\u2009=\u20090.93; 95% CI, 0.89\u20130.96), ischemic stroke recurrence (HR\u2009=\u20090.92; 95% CI, 0.87\u20130.98), and composite vascular events (HR =0.94; 95% CI, 0.89\u20130.99) at 1\u2009year. Faster gait speed at 3\u2009months was associated with lower incidence of poor functional outcome (OR\u2009=\u20090.90; 95% CI, 0.85\u20130.95), ambulate dependency (OR\u2009=\u20090.86; 95% CI, 0.77\u20130.97), and cognitive impairment (OR\u2009=\u20090.92; 95% CI, 0.88\u20130.95) at 1\u2009year.<\/jats:p><\/jats:sec><jats:sec><jats:title>Interpretation<\/jats:title><jats:p>Our findings indicated that slow gait speed after minor stroke or TIA may be an independent predictor for long\u2010term poor outcomes. Gait speed may be considered as a vital sign during follow\u2010up in post\u2010stroke patients.<\/jats:p><\/jats:sec>","DOI":"10.1002\/acn3.52222","type":"journal-article","created":{"date-parts":[[2024,10,12]],"date-time":"2024-10-12T06:03:27Z","timestamp":1728713007000},"page":"3163-3174","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Gait speed after mild stroke\/transient ischemic attack was associated with long\u2010term adverse outcomes: A cohort study"],"prefix":"10.1002","volume":"11","author":[{"given":"Ning","family":"Li","sequence":"first","affiliation":[{"name":"Department of Neurology, Beijing Tiantan Hospital Capital Medical University  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jia","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Neurology, Beijing Tiantan Hospital Capital Medical University  Beijing China"},{"name":"China National 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