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We present a series of three patients under 55\u2009years of age who underwent cranial surgery. All of them developed multiple cerebral hemorrhages, transient focal neurological deficits, and\/or cognitive impairment after 3\u20134 decades. MRI was compatible with CAA, and A\u03b2 deposition was confirmed. The third patient, who had a ventriculoperitoneal valve, also showed A\u03b2 deposition in the peritoneum and diagnostic biomarkers of Alzheimer's disease. Co\u2010pathology with Alzheimer disease and its iatrogenic transmission should be considered.<\/jats:p>","DOI":"10.1002\/acn3.52278","type":"journal-article","created":{"date-parts":[[2024,12,27]],"date-time":"2024-12-27T21:43:52Z","timestamp":1735335832000},"page":"235-241","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Iatrogenic cerebral amyloid angiopathy and Alzheimer's disease co\u2010pathology"],"prefix":"10.1002","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6681-2683","authenticated-orcid":false,"given":"Francisco","family":"Hern\u00e1ndez\u2010Fern\u00e1ndez","sequence":"first","affiliation":[{"name":"Neurology Department Albacete Universitary Hospital  Albacete Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabel","family":"Mart\u00ednez\u2010Fern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Neurology Department Albacete Universitary Hospital  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