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A 63\u2010year\u2010old woman presenting with a 3\u2010year history of apathy and memory impairment showed executive dysfunction, memory impairment, and severe bilateral frontotemporal atrophy on MRI. A\u03b2 PET showed only equivocal findings in the right frontal lobe and was negative. However, CSF showed a severely decreased A\u03b242\/40 ratio and increased phospho\u2010tau181. AD\u2010tau\u2010specific (18F)\u2010MK6240 PET revealed increased tracer retention predominantly in the bilateral frontal lobes, confirming the fvAD diagnosis. 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