{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:19:04Z","timestamp":1786976344665,"version":"build-2736575974"},"reference-count":41,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,4,3]],"date-time":"2025-04-03T00:00:00Z","timestamp":1743638400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82201634"],"award-info":[{"award-number":["82201634"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ann Clin Transl Neurol"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Deep brain stimulation offers a unique opportunity to record neural activity of the basal ganglia. While much work in dystonia has focused on the globus pallidus internus, expanding research to investigate subthalamic nucleus (STN) activity in various dystonia types is critical to provide a comprehensive understanding of dystonia pathophysiology.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>STN and cortex activity were recorded from 17 patients with cervical dystonia (CD), 19 with Meige syndrome, and 9 with generalized dystonia (GD) during the lead externalized period. We investigated local and network oscillatory characteristics, including power, bursts, and coherence. Additionally, we explored the relationship between these features and the severity of dystonic symptoms within each group and conducted a comparative analysis across the different dystonia types.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Peaks of low\u2010frequency (4\u201313\u2009Hz) and beta (14\u201330\u2009Hz) power were present in the STN of all patients; most of the beta peaks are distributed in the high beta range (20\u201330\u2009Hz). The CD and GD groups showed longer low\u2010frequency bursts and greater high beta power in STN than the Meige group. Interestingly, the CD group showed stronger STN\u2010cortex low\u2010frequency coherence, while the GD group had stronger STN\u2010cortex high beta coherence. Combined, low\u2010frequency and beta features could predict symptom severity with a performance of 73% in the CD group and 82% in the GD group.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Interpretation<\/jats:title>\n                    <jats:p>Low\u2010frequency and high\u2010beta oscillations are present in the STN across all three types of dystonia. The distinct patterns may be associated with different underlying pathological mechanisms.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/acn3.70040","type":"journal-article","created":{"date-parts":[[2025,4,5]],"date-time":"2025-04-05T01:18:13Z","timestamp":1743815893000},"page":"1082-1092","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Subthalamic Nucleus Oscillatory Characteristics in Meige, Cervical Dystonia and Generalized Dystonia"],"prefix":"10.1002","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8679-7473","authenticated-orcid":false,"given":"Zhu","family":"Guan\u2010Yu","sequence":"first","affiliation":[{"name":"Department of Neurosurgery Beijing Tiantan Hospital, Capital Medical University  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yin","family":"Zi\u2010Xiao","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery Beijing Tiantan Hospital, Capital Medical University  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chen","family":"Ying\u2010Chuan","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery Beijing Tiantan Hospital, Capital Medical University  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timon","family":"Merk","sequence":"additional","affiliation":[{"name":"Movement Disorder and Neuromodulation Unit, Department of Neurology Charit\u00e9\u2014Universit\u00e4tsmedizin  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Binns","sequence":"additional","affiliation":[{"name":"Movement Disorder and Neuromodulation Unit, Department of Neurology Charit\u00e9\u2014Universit\u00e4tsmedizin  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ma","family":"Ruo\u2010Yu","sequence":"additional","affiliation":[{"name":"Department of 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