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In this pilot study, 19 patients with recent\u2010onset (\u2264\u200918\u2009months) cognitive impairment underwent skin biopsy at baseline, with follow\u2010up clinical re\u2010evaluation. Five patients fulfilled the Dementia with Lewy bodies diagnosis, all of them positive for skin phosphorylated alpha\u2010synuclein. The remaining 14 patients were all negative. 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