{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,10]],"date-time":"2026-01-10T17:12:53Z","timestamp":1768065173052,"version":"3.49.0"},"reference-count":10,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T00:00:00Z","timestamp":1759449600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100009398","name":"Medizinische Fakult\u00e4t, RWTH Aachen University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100009398","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ann Clin Transl Neurol"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Friedreich's ataxia is a multisystem disorder with scoliosis being the most common non\u2010neurological manifestation. While scoliosis surgery is typically performed in adolescent, ambulatory patients, few data exist on surgical outcomes in patients with advanced disease. We present a 38\u2010year\u2010old woman with late\u2010stage Friedreich's ataxia and pronounced thoracolumbar scoliosis (Cobb angle 48\u00b0) causing severe pain and limited sitting tolerance. After posterior corrective spondylodesis (T4\u2010ilium), she reported marked improvements in pain, sitting tolerance, function, and quality of life in the SF\u201036 questionnaire. This case highlights the potential for substantial clinical and functional benefits from scoliosis surgery in patients with advanced Friedreich's ataxia.<\/jats:p>","DOI":"10.1002\/acn3.70219","type":"journal-article","created":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T02:22:26Z","timestamp":1759544546000},"page":"200-203","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Scoliosis Surgery in a Patient With Advanced Friedreich's Ataxia\u2014It Is Not Too Late"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9730-9228","authenticated-orcid":false,"given":"Kathrin","family":"Reetz","sequence":"first","affiliation":[{"name":"Department of Neurology RWTH Aachen University  Aachen Germany"},{"name":"JARA\u2010BRAIN Institute Molecular Neuroscience and Neuroimaging Research Centre Juelich GmbH and RWTH Aachen University  Aachen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1165-9153","authenticated-orcid":false,"given":"Stella A.","family":"Lischewski","sequence":"additional","affiliation":[{"name":"Department of Neurology RWTH Aachen University  Aachen Germany"},{"name":"JARA\u2010BRAIN Institute Molecular Neuroscience and Neuroimaging Research Centre Juelich GmbH and RWTH Aachen University  Aachen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8903-0593","authenticated-orcid":false,"given":"J\u00f6rg B.","family":"Schulz","sequence":"additional","affiliation":[{"name":"Department of Neurology RWTH Aachen University  Aachen Germany"},{"name":"JARA\u2010BRAIN Institute Molecular Neuroscience and Neuroimaging Research Centre Juelich GmbH and RWTH Aachen University  Aachen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maximilian","family":"Praster","sequence":"additional","affiliation":[{"name":"Department for Orthopaedics, Trauma and Reconstructive Surgery RWTH Aachen University Hospital  Aachen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miguel","family":"Pishnamaz","sequence":"additional","affiliation":[{"name":"Department for Orthopaedics, Trauma and Reconstructive Surgery RWTH Aachen University Hospital  Aachen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"the FACROSS study group","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Imis","family":"Dogan","sequence":"additional","affiliation":[{"name":"Department of Neurology RWTH Aachen University  Aachen Germany"},{"name":"JARA\u2010BRAIN Institute Molecular Neuroscience and Neuroimaging Research Centre Juelich GmbH and RWTH Aachen University  Aachen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8519-1309","authenticated-orcid":false,"given":"Sandro","family":"Romanzetti","sequence":"additional","affiliation":[{"name":"Department of Neurology RWTH Aachen University  Aachen Germany"},{"name":"JARA\u2010BRAIN Institute Molecular Neuroscience and Neuroimaging Research Centre Juelich GmbH and RWTH Aachen University  Aachen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7387-0750","authenticated-orcid":false,"given":"Ravi","family":"Dadsena","sequence":"additional","affiliation":[{"name":"Department of Neurology RWTH Aachen University  Aachen Germany"},{"name":"JARA\u2010BRAIN Institute Molecular Neuroscience and Neuroimaging Research Centre Juelich GmbH and RWTH Aachen University  Aachen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kerstin","family":"Konrad","sequence":"additional","affiliation":[{"name":"Section Child Neuropsychology, Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy RWTH Aachen, University Hospital  Aachen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Clavel","sequence":"additional","affiliation":[{"name":"Functional Microbiome Research Group, Institute of Medical Microbiology RWTH University Hospital  Aachen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vera","family":"Jankowski","sequence":"additional","affiliation":[{"name":"Institute for Molecular Cardiovascular Research RWTH Aachen University Hospital  Aachen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joachim","family":"Jankowski","sequence":"additional","affiliation":[{"name":"Institute for Molecular Cardiovascular Research RWTH Aachen University Hospital  Aachen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oliver","family":"Pabst","sequence":"additional","affiliation":[{"name":"Institute of Molecular Medicine RWTH Aachen University  Aachen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nikolaus","family":"Marx","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine I, Cardiology RWTH Aachen University  Aachen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julia","family":"Moellmann","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine I, Cardiology RWTH Aachen University  Aachen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Malte","family":"Jacobsen","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine I, Cardiology RWTH Aachen University  Aachen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katharina","family":"Marx\u2010Sch\u00fctt","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine I, Cardiology RWTH Aachen University  Aachen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juergen","family":"Dukart","sequence":"additional","affiliation":[{"name":"Institute of Neuroscience and Medicine, Brain and Behaviour (INM\u20107), RResearch Centre J\u00fclich  J\u00fclich Germany"},{"name":"Institute of Systems Neuroscience Medical Faculty, Heinrich Heine University D\u00fcsseldorf  D\u00fcsseldorf Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simon","family":"Eickhoff","sequence":"additional","affiliation":[{"name":"Institute of Neuroscience and Medicine, Brain and Behaviour (INM\u20107), RResearch Centre J\u00fclich  J\u00fclich Germany"},{"name":"Institute of Systems Neuroscience Medical Faculty, Heinrich Heine University D\u00fcsseldorf  D\u00fcsseldorf Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ralf\u2010Dieter","family":"Hilgers","sequence":"additional","affiliation":[{"name":"Department of Medical Statistics RWTH Aachen University  Aachen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,10,3]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/acn3.51352"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jspd.2019.02.005"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/BPO.0b013e318164fa79"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1302\/0301\u2010620x.94b5.28391"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1212\/wnl.0000000000006121"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00586\u2010023\u201007943\u20107"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00132\u2010021\u201004128\u20102"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/bpo.0000000000000396"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.Wnl.0000156802.15466.79"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00586\u2010024\u201008338\u2010y"}],"container-title":["Annals of Clinical and Translational Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/acn3.70219","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,10]],"date-time":"2026-01-10T14:17:59Z","timestamp":1768054679000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/acn3.70219"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,3]]},"references-count":10,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1002\/acn3.70219"],"URL":"https:\/\/doi.org\/10.1002\/acn3.70219","archive":["Portico"],"relation":{},"ISSN":["2328-9503","2328-9503"],"issn-type":[{"value":"2328-9503","type":"print"},{"value":"2328-9503","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10,3]]},"assertion":[{"value":"2025-04-17","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-09-15","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-03","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}