{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T22:24:58Z","timestamp":1789770298501,"version":"4.0.1"},"reference-count":48,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,11,17]],"date-time":"2025-11-17T00:00:00Z","timestamp":1763337600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,11,17]],"date-time":"2025-11-17T00:00:00Z","timestamp":1763337600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ann Clin Transl Neurol"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Optical coherence tomography (OCT)\u2010derived retina measurements are markers for neuroaxonal visual pathway status. High\u2010quality OCT scans are essential for reliable measurements, but their acquisition is particularly challenging in eyes with severe visual impairment, as often observed in neuromyelitis optica spectrum disorders (NMOSD).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To investigate OCT quality issues in real\u2010world data from the international Collaborative Retrospective Study on Retinal OCT in Neuromyelitis Optica (CROCTINO).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We evaluated the quality of peripapillary and macular OCT scans, using Heidelberg Spectralis SD\u2010OCT, Carl Zeiss Cirrus HD\u2010OCT, or Topcon SD\u2010OCT across 22 centers. Experienced graders applied OSCAR\u2010IB criteria for OCT quality. Eyes were classified as severely visually impaired or not based on a 1.0 logMAR cut\u2010off. Quality outcomes were compared using the Chi\u2010square test.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 3075 OCT scans (1630 peripapillary, 1445 macular) from 539 people with NMOSD and related conditions were evaluated. Macular scans were rejected more often than peripapillary scans due to quality issues (20.1% vs. 14.5%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Rejection rates were higher in eyes with severe visual impairment (peripapillary: 28.9%, macular: 41.6%) compared to eyes without severe visual impairment (peripapillary: 10.7%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001; macular: 14.6%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Our study revealed that approximately one in six scans was rejected due to low quality, with higher rejection rates in eyes with severe visual impairment. As scan quality can bias quantitative outcomes and artificial intelligence applications, these findings emphasize the unmet need for standardized OCT practices tailored to NMOSD and other conditions involving severe visual impairment.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/acn3.70235","type":"journal-article","created":{"date-parts":[[2025,11,17]],"date-time":"2025-11-17T11:23:04Z","timestamp":1763378584000},"page":"581-592","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Lessons Learned: Quality Analysis of Optical Coherence Tomography in Neuromyelitis Optica"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-0889-9361","authenticated-orcid":false,"given":"Hadi","family":"Salih","sequence":"first","affiliation":[{"name":"Experimental and Clinical Research Center, Max Delbr\u00fcck Center for Molecular Medicine and Charit\u00e9\u2014Universit\u00e4tsmedizin Berlin, Corporate Member of Freie Universit\u00e4t Berlin and Humboldt\u2010Universit\u00e4t zu Berlin  Berlin Germany"},{"name":"Neuroscience Clinical Research Center, Charit\u00e9\u2014Universit\u00e4tsmedizin Berlin, Corporate Member of Freie Universit\u00e4t Berlin and Humboldt\u2010Universit\u00e4t zu Berlin  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Samadzadeh","sequence":"additional","affiliation":[{"name":"Experimental and Clinical Research Center, Max Delbr\u00fcck Center for Molecular Medicine and Charit\u00e9\u2014Universit\u00e4tsmedizin Berlin, Corporate Member of Freie Universit\u00e4t Berlin and Humboldt\u2010Universit\u00e4t zu Berlin  Berlin Germany"},{"name":"Neuroscience Clinical Research Center, Charit\u00e9\u2014Universit\u00e4tsmedizin Berlin, Corporate Member of Freie Universit\u00e4t Berlin and Humboldt\u2010Universit\u00e4t zu Berlin  Berlin Germany"},{"name":"Institute of Regional Health Research University of Southern Denmark  Odense Denmark"},{"name":"Department of Neurology, The Center for Neurological Research Slagelse Hospitals  Slagelse Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charlotte","family":"Bereuter","sequence":"additional","affiliation":[{"name":"Experimental and Clinical Research Center, Max Delbr\u00fcck Center for Molecular Medicine and Charit\u00e9\u2014Universit\u00e4tsmedizin Berlin, Corporate Member of Freie Universit\u00e4t Berlin and Humboldt\u2010Universit\u00e4t zu Berlin  Berlin Germany"},{"name":"Neuroscience Clinical Research Center, Charit\u00e9\u2014Universit\u00e4tsmedizin Berlin, Corporate Member of Freie Universit\u00e4t Berlin and Humboldt\u2010Universit\u00e4t zu Berlin  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6897-5387","authenticated-orcid":false,"given":"Seyedamirhosein","family":"Motamedi","sequence":"additional","affiliation":[{"name":"Experimental and Clinical Research Center, Max Delbr\u00fcck Center for Molecular Medicine and Charit\u00e9\u2014Universit\u00e4tsmedizin Berlin, Corporate Member of Freie Universit\u00e4t Berlin and Humboldt\u2010Universit\u00e4t zu Berlin  Berlin Germany"},{"name":"Neuroscience Clinical Research Center, Charit\u00e9\u2014Universit\u00e4tsmedizin Berlin, Corporate Member of Freie Universit\u00e4t Berlin and Humboldt\u2010Universit\u00e4t zu Berlin  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8280-9513","authenticated-orcid":false,"given":"Claudia","family":"Chien","sequence":"additional","affiliation":[{"name":"Experimental and Clinical Research Center, Max Delbr\u00fcck Center for Molecular Medicine and Charit\u00e9\u2014Universit\u00e4tsmedizin Berlin, Corporate Member of Freie Universit\u00e4t Berlin and Humboldt\u2010Universit\u00e4t zu Berlin  Berlin Germany"},{"name":"Neuroscience Clinical Research Center, Charit\u00e9\u2014Universit\u00e4tsmedizin Berlin, Corporate Member of Freie Universit\u00e4t Berlin and Humboldt\u2010Universit\u00e4t zu Berlin  Berlin Germany"},{"name":"Department of Psychiatry and Neurosciences Charit\u00e9\u2014Universit\u00e4tsmedizin Berlin, Corporate Member of Freie Universit\u00e4t Berlin and Humboldt\u2010Universit\u00e4t zu Berlin  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8735-6119","authenticated-orcid":false,"given":"Pablo","family":"Villoslada","sequence":"additional","affiliation":[{"name":"Department of Neurology Hospital del Mar\u2014Pompeu Fabra University  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hadas","family":"Stiebel\u2010Kalish","sequence":"additional","affiliation":[{"name":"Neuro\u2010Ophthalmology Division, Department of Ophthalmology Rabin Medical Center  Tel Aviv Israel"},{"name":"Eye Laboratory, Felsenstein Medical Research Center Tel Aviv University  Tel Aviv Israel"},{"name":"Faculty of Medicine Tel Aviv University  Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8551-0947","authenticated-orcid":false,"given":"Nasrin","family":"Asgari","sequence":"additional","affiliation":[{"name":"Department of Neurology Slagelse Hospitals  Slagelse Denmark"},{"name":"Institute of Regional Health Research and Molecular Medicine University of Southern Denmark  Odense Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Mao\u2010Draayer","sequence":"additional","affiliation":[{"name":"Autoimmunity Center of Excellence, Multiple Sclerosis Center of Excellence, Arthritis and Clinical Immunology, Oklahoma Medical Research Foundation  Oklahoma City Oklahoma USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3618-8407","authenticated-orcid":false,"given":"Marius","family":"Ringelstein","sequence":"additional","affiliation":[{"name":"Department of Neurology University Clinic and Medical Faculty, Heinrich Heine University D\u00fcsseldorf  D\u00fcsseldorf Germany"},{"name":"Department of Neurology Center for Neurology and Neuropsychiatry, LVR\u2010Klinikum, Heinrich\u2010Heine\u2010University D\u00fcsseldorf  D\u00fcsseldorf Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4386-1340","authenticated-orcid":false,"given":"Joachim","family":"Havla","sequence":"additional","affiliation":[{"name":"Institute of Clinical Neuroimmunology, LMU Hospital, Ludwig\u2010Maximilians\u2010University Munich  Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco Aur\u00e9lio Lana","family":"Peixoto","sequence":"additional","affiliation":[{"name":"CIEM MS Research Center\u2014Federal University of Minas Gerais  Belo Horizonte Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8672-8419","authenticated-orcid":false,"given":"Ho Jin","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Neurology National Cancer Center  Goyang Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacqueline","family":"Palace","sequence":"additional","affiliation":[{"name":"Department of Neurology Oxford University Hospitals, National Health Service Trust  Oxford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Isabel","family":"Leite","sequence":"additional","affiliation":[{"name":"Department of Neurology Oxford University Hospitals, National Health Service Trust  Oxford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Srilakshmi M.","family":"Sharma","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Oxford University Hospitals, National Health Service Trust  Oxford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fereshteh","family":"Ashtari","sequence":"additional","affiliation":[{"name":"Kashani MS Center, Isfahan Neuroscience Research Center Isfahan University of Medical Sciences  Isfahan Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rahele","family":"Kafieh","sequence":"additional","affiliation":[{"name":"Department of Engineering Durham University  Durham UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2269-5312","authenticated-orcid":false,"given":"Lekha","family":"Pandit","sequence":"additional","affiliation":[{"name":"Center for Advanced Neurological Research, KS Hegde Medical Academy Nitte University  Mangalore India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Orhan","family":"Aktas","sequence":"additional","affiliation":[{"name":"Department of Neurology University Clinic and Medical Faculty, Heinrich Heine University D\u00fcsseldorf  D\u00fcsseldorf Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7987-658X","authenticated-orcid":false,"given":"Philipp","family":"Albrecht","sequence":"additional","affiliation":[{"name":"Department of Neurology University Clinic and Medical Faculty, Heinrich Heine University D\u00fcsseldorf  D\u00fcsseldorf Germany"},{"name":"Department of Neurology Kliniken Maria Hilf GmbH M\u00f6nchengladbach  M\u00f6nchengladbach Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9326-6753","authenticated-orcid":false,"given":"Letizia","family":"Leocani","sequence":"additional","affiliation":[{"name":"Department of Medicine Los Angeles Biomedical Research Institute at Harbor\u2010University of California at Los Angeles (UCLA) Medical Center  Torrance California USA"},{"name":"IRCSS Scientific Institute San Raffaele  Milan Italy"},{"name":"Department of Neurorehabilitation Sciences Casa di Cura Igea  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Itay","family":"Lotan","sequence":"additional","affiliation":[{"name":"Department of Neurology Rabin Medical Center, Faculty of Medicine, Tel Aviv University  Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sasitorn","family":"Siritho","sequence":"additional","affiliation":[{"name":"Division of Neurology, Department of Medicine, Siriraj Neuroimmunology Center Siriraj Hospital and Bumrungrad International Hospital  Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00e9r\u00f4me","family":"de Seze","sequence":"additional","affiliation":[{"name":"Neurology Service, University Hospital of Strasbourg  Strasbourg France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5967-2800","authenticated-orcid":false,"given":"Romain","family":"Marignier","sequence":"additional","affiliation":[{"name":"Neurology, Multiple Sclerosis, Myelin Disorders and Neuroinflammation, Pierre Wertheimer Neurological Hospital, Hospices Civils de Lyon  Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline Froment","family":"Tilikete","sequence":"additional","affiliation":[{"name":"Department of Neuro\u2010Ophthalmology Hospices Civils de Lyon  Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denis Bernardi","family":"Bichuetti","sequence":"additional","affiliation":[{"name":"Departamento de Neurologia e Neurocirurgia Escola Paulista de Medicina, Universidade Federal de S\u00e3o Paulo  S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivan Maynart","family":"Tavares","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology and Visual Sciences Escola Paulista de Medicina, Universidade Federal de S\u00e3o Paulo  S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayse","family":"Altintas","sequence":"additional","affiliation":[{"name":"Neurology Department, School of Medicine Koc University  Istanbul Turkey"},{"name":"Neurology Department, Cerrahpasa School of Medicine Istanbul University  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anu","family":"Jacob","sequence":"additional","affiliation":[{"name":"The Walton Centre for Neurology and Neurosurgery  Liverpool UK"},{"name":"Cleveland Clinic Abu Dhabi  Abu Dhabi UAE"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saif","family":"Huda","sequence":"additional","affiliation":[{"name":"Department of Pharmacology and Therapeutics Institute of Systems, Molecular and Integrative Biology, University of Liverpool  Liverpool UK"},{"name":"Department of Neurology The Walton Centre NHS Foundation Trust  Liverpool UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ibis Soto","family":"de Castillo","sequence":"additional","affiliation":[{"name":"Department of Neurology Hospital Clinico de Maracaibo  Maracaibo Venezuela"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lawrence J.","family":"Cook","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University of Utah  Salt Lake City Utah USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael R.","family":"Yeaman","sequence":"additional","affiliation":[{"name":"Department of Medicine David Geffen School of Medicine at UCLA  Los Angeles California USA"},{"name":"Department of Medicine, Divisions of Molecular Medicine and Infectious Diseases Harbor\u2010UCLA Medical Center  Torrance California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Axel","family":"Petzold","sequence":"additional","affiliation":[{"name":"Department of Neuroinflammation Queen Square MS Centre, Faculty of Brain Sciences, UCL Queen Square Institute of Neurology  London UK"},{"name":"Moorfields Eye Hospital and The National Hospital for Neurology and Neurosurgery University College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9768-014X","authenticated-orcid":false,"given":"Alexander U.","family":"Brandt","sequence":"additional","affiliation":[{"name":"Experimental and Clinical Research Center, Max Delbr\u00fcck Center for Molecular Medicine and Charit\u00e9\u2014Universit\u00e4tsmedizin Berlin, Corporate Member of Freie Universit\u00e4t Berlin and Humboldt\u2010Universit\u00e4t zu Berlin  Berlin Germany"},{"name":"Neuroscience Clinical Research Center, Charit\u00e9\u2014Universit\u00e4tsmedizin Berlin, Corporate Member of Freie Universit\u00e4t Berlin and Humboldt\u2010Universit\u00e4t zu Berlin  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6378-0070","authenticated-orcid":false,"given":"Friedemann","family":"Paul","sequence":"additional","affiliation":[{"name":"Experimental and Clinical Research Center, Max Delbr\u00fcck Center for Molecular Medicine and Charit\u00e9\u2014Universit\u00e4tsmedizin Berlin, Corporate Member of Freie Universit\u00e4t Berlin and Humboldt\u2010Universit\u00e4t zu Berlin  Berlin Germany"},{"name":"Neuroscience Clinical Research Center, Charit\u00e9\u2014Universit\u00e4tsmedizin Berlin, Corporate Member of Freie Universit\u00e4t Berlin and Humboldt\u2010Universit\u00e4t zu Berlin  Berlin Germany"},{"name":"Department of Neurology Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin, Corporate Member of Freie Universit\u00e4t Berlin, Humboldt\u2010Universit\u00e4t zu Berlin, and Berlin Institute of Health  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4906-5983","authenticated-orcid":false,"given":"Frederike C.","family":"Oertel","sequence":"additional","affiliation":[{"name":"Experimental and Clinical Research Center, Max Delbr\u00fcck Center for Molecular Medicine and Charit\u00e9\u2014Universit\u00e4tsmedizin Berlin, Corporate Member of Freie Universit\u00e4t Berlin and Humboldt\u2010Universit\u00e4t zu Berlin  Berlin Germany"},{"name":"Neuroscience Clinical Research Center, Charit\u00e9\u2014Universit\u00e4tsmedizin Berlin, Corporate Member of Freie Universit\u00e4t Berlin and Humboldt\u2010Universit\u00e4t zu Berlin  Berlin Germany"},{"name":"Department of Neurology Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin, Corporate Member of Freie Universit\u00e4t Berlin, Humboldt\u2010Universit\u00e4t zu Berlin, and Berlin Institute of Health  Berlin Germany"},{"name":"Einstein Center Digital Future  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0276-8051","authenticated-orcid":false,"given":"Hanna G.","family":"Zimmermann","sequence":"additional","affiliation":[{"name":"Experimental and Clinical Research Center, Max Delbr\u00fcck Center for Molecular Medicine and Charit\u00e9\u2014Universit\u00e4tsmedizin Berlin, Corporate Member of Freie Universit\u00e4t Berlin and Humboldt\u2010Universit\u00e4t zu Berlin  Berlin Germany"},{"name":"Neuroscience Clinical Research Center, Charit\u00e9\u2014Universit\u00e4tsmedizin Berlin, Corporate Member of Freie Universit\u00e4t Berlin and Humboldt\u2010Universit\u00e4t zu Berlin  Berlin Germany"},{"name":"Einstein Center Digital Future  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"with the Guthy Jackson Charitable Foundation\u2014International Clinical Consortium and CROCTINO Collaborators","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,11,17]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000001729"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(22)00431-8"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ncl.2023.06.009"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41572-020-0214-9"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13167-017-0123-5"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sjopt.2014.02.010"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1080\/01658107.2016.1238487"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/aos.12762"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2007.11.027"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1080\/02713683.2023.2223869"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0034823"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1177\/1352458514538110"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2019-035397"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1212\/NXI.0000000000001068"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.26440"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1212\/NXI.0000000000200273"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp-2021-327412"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/WNO.0000000000001991"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1212\/NXI.0000000000200291"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp-2022-330608"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-04268-3_13"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1364\/OE.20.006761"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.08-2988"},{"issue":"3","key":"e_1_2_11_25_1","first-page":"207","article-title":"Role of OCT in Diagnosis and Progression of Glaucoma","volume":"34","author":"Mahar P. S.","year":"2018","journal-title":"Pakistan Journal of Ophthalmology"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2019.01117"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2005.10.005"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2004.07.050"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.07-1326"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2007.114074"},{"key":"e_1_2_11_31_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0048222"},{"key":"e_1_2_11_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbi.2008.08.010"},{"key":"e_1_2_11_33_1","unstructured":"R Core Team \u201cR: A Language and Environment for Statistical Computing \u201d(2021) https:\/\/www.r\u2010project.org."},{"key":"e_1_2_11_34_1","doi-asserted-by":"publisher","DOI":"10.1364\/OE.17.004019"},{"key":"e_1_2_11_35_1","doi-asserted-by":"publisher","DOI":"10.1097\/IJG.0b013e31817eee20"},{"key":"e_1_2_11_36_1","doi-asserted-by":"publisher","DOI":"10.4274\/tjo.galenos.2019.78000"},{"key":"e_1_2_11_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2009.10.029"},{"key":"e_1_2_11_38_1","doi-asserted-by":"publisher","DOI":"10.1111\/aos.13443"},{"key":"e_1_2_11_39_1","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.125.5.624"},{"key":"e_1_2_11_40_1","doi-asserted-by":"publisher","DOI":"10.1007\/7651_2014_153"},{"key":"e_1_2_11_41_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaophthalmol.2013.7974"},{"key":"e_1_2_11_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2009.03.034"},{"key":"e_1_2_11_43_1","doi-asserted-by":"publisher","DOI":"10.1097\/IAE.0b013e3181c2e09d"},{"key":"e_1_2_11_44_1","doi-asserted-by":"publisher","DOI":"10.1364\/BOE.487518"},{"key":"e_1_2_11_45_1","first-page":"2549839","volume-title":"Medical Imaging 2020: Image Processing","author":"He Y.","year":"2020"},{"key":"e_1_2_11_46_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-43958-1"},{"key":"e_1_2_11_47_1","doi-asserted-by":"publisher","DOI":"10.1364\/BOE.551186"},{"key":"e_1_2_11_48_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0162015"},{"key":"e_1_2_11_49_1","doi-asserted-by":"publisher","DOI":"10.1167\/tvst.12.11.12"}],"updated-by":[{"DOI":"10.1002\/acn3.70491","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2026,7,26]],"date-time":"2026-07-26T00:00:00Z","timestamp":1785024000000}}],"container-title":["Annals of Clinical and Translational Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/acn3.70235","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/acn3.70235","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/acn3.70235","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T06:44:41Z","timestamp":1773038681000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/acn3.70235"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,17]]},"references-count":48,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,3]]}},"alternative-id":["10.1002\/acn3.70235"],"URL":"https:\/\/doi.org\/10.1002\/acn3.70235","archive":["Portico"],"relation":{},"ISSN":["2328-9503","2328-9503"],"issn-type":[{"value":"2328-9503","type":"print"},{"value":"2328-9503","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,17]]},"assertion":[{"value":"2025-03-30","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-09-30","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-17","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}