{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T04:49:44Z","timestamp":1776055784651,"version":"3.50.1"},"reference-count":44,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T00:00:00Z","timestamp":1767139200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T00:00:00Z","timestamp":1767139200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ann Clin Transl Neurol"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>The practice of neurology requires an understanding of clinical ethics for decision\u2010making. In multiple sclerosis (MS) care, there are a wide range of ethical considerations that may arise. These involve shared decision\u2010making around selection of a disease\u2010modifying therapy (DMT), risks and benefits of well\u2010studied medications in comparison to supplements with limited information, allocation of resources and accessibility to MS care, and disparities in healthcare. We share a series of cases that illustrate ethical issues that may arise in the care of patients with MS. This narrative review articulates relevant ethical theories and frameworks that can be applied to common clinical scenarios in the current practice of MS.<\/jats:p>","DOI":"10.1002\/acn3.70302","type":"journal-article","created":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T02:33:53Z","timestamp":1767234833000},"page":"850-859","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Applying an Ethical Lens to the Treatment of People With Multiple Sclerosis"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5225-7006","authenticated-orcid":false,"given":"Methma","family":"Udawatta","sequence":"first","affiliation":[{"name":"Massachusetts General Hospital  Boston Massachusetts USA"},{"name":"Brigham and Women's Hospital  Boston Massachusetts USA"},{"name":"Harvard Medical School  Boston Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4293-8115","authenticated-orcid":false,"given":"Farrah J.","family":"Mateen","sequence":"additional","affiliation":[{"name":"Ken and Ruth Davee Department of Neurology Northwestern University  Chicago Illinois USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,12,31]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.135.1.22"},{"key":"e_1_2_12_3_1","volume-title":"The Stanford Encyclopedia of Philosophy","author":"Norlock K.","year":"2019"},{"key":"e_1_2_12_4_1","volume-title":"The Stanford Encyclopedia of Philosophy","author":"Alexander L.","year":"2007"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1159\/000509119"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.33.11.1444"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474\u20104422(25)00270\u20104"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2017.04.010"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2021.693017"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474\u20104422(20)30067\u20103"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2018.20588"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1601277"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.msard.2023.104630"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.msard.2020.102485"},{"key":"e_1_2_12_15_1","volume-title":"Principles of Biomedical Ethics","author":"Beauchamp T. 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