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<jats:p>Diffuse axonal injury (DAI) is caused by acceleration\u2010deceleration forces during trauma that shear white matter tracts. Susceptibility\u2010weighted MRI (SWI) identifies microbleeds that are considered the radiologic hallmark of DAI and are used in clinical prognostication. However, this assumption is limited by a lack of systematic radiologic\u2010pathologic correlation studies. Here, we performed ex\u00a0vivo SWI on three brains from patients who died after severe TBI and assessed axonal injury around SWI microbleeds using immunohistochemistry to the amyloid\u2010beta precursor protein. 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