{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T00:24:18Z","timestamp":1765758258846,"version":"build-2065373602"},"reference-count":34,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2010,2,26]],"date-time":"2010-02-26T00:00:00Z","timestamp":1267142400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arthritis Care &amp;amp; Research"],"published-print":{"date-parts":[[2010,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To compare the reliability of 3 different simplified joint counts with the gold standard 66 swollen\/68 tender joint count (JC66\/68) for assessing clinical response in patients with polyarticular psoriatic arthritis (PsA).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The 28\u2013joint count (JC28), in the same way that it is used in rheumatoid arthritis, and 2 measures including distal interphalangeal (DIP) joints (the 32\u2013joint count [JC32], including all finger joints as well as wrists and knees, and 36\u2013joint count [JC36], which additionally included elbows and ankles), were compared with the JC66\/68 in 182 patients using data from the Infliximab Multinational Psoriatic Arthritis Controlled Trial 2 trial database. Pearson's correlation coefficients were calculated to compare the swollen and tender JC28, JC32, and JC36 with the corresponding results of the total JC66\/68. American College of Rheumatology (ACR) responses based on the individual measures were compared, and their ability in predicting a clinical response of ACR 20% improvement (ACR20) based on the JC66\/68 was assessed by calculating the area under the receiver operating characteristic curve via logistic regression and the maximum Youden indices at weeks 14 and 24.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>All simplified joint counts were highly correlated to the standard JC66\/68 both for tenderness and swelling at each individual visit (Pearson's correlation coefficients consistently &gt;0.8, n = 182\u2013200; <jats:italic>P<\/jats:italic> &lt; 0.0001). Logistic regression for ACR20 response showed that area under the curve was constantly &gt;0.91, with comparable results for Youden indices of the simplified joint counts.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>All simplified joint counts considered seemed sufficiently sensitive and specific to measure clinical response in trial patients with polyarticular PsA when compared with the JC66\/68, no matter whether DIP joints were included (the JC36 and JC32) or excluded (the JC28). Further research will be needed to clarify this issue.<\/jats:p><\/jats:sec>","DOI":"10.1002\/acr.20161","type":"journal-article","created":{"date-parts":[[2010,2,26]],"date-time":"2010-02-26T18:50:38Z","timestamp":1267210238000},"page":"977-983","source":"Crossref","is-referenced-by-count":15,"title":["Measuring joint involvement in polyarticular psoriatic arthritis: An introduction of alternatives"],"prefix":"10.1002","volume":"62","author":[{"given":"M.","family":"Englbrecht","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y.","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Ronneberger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Manger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Vastesaeger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. 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