{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T15:14:42Z","timestamp":1779290082748,"version":"3.51.4"},"reference-count":12,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2011,2,25]],"date-time":"2011-02-25T00:00:00Z","timestamp":1298592000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arthritis Care &amp; Research"],"published-print":{"date-parts":[[2011,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To verify whether magnetic resonance imaging (MRI)\u2013proven joint injury is sensitive as compared with joint injury determined by physical examination.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>MRI of the wrist and finger joints of both hands was examined in 51 early\u2010stage rheumatoid arthritis (RA) patients by both plain and gadolinium diethylenetriaminepentaacetic acid\u2013enhanced MRI. Synovitis, bone edema, and bone erosion (the latter two included as bone lesions at the wrist joints); metacarpophalangeal joints; and proximal interphalangeal joints were considered as MRI\u2010proven joint injury. Japan College of Rheumatology\u2013certified rheumatologists had given a physical examination just before the MRI study. The presence of tender and\/or swollen joints in the same fields as MRI was considered as joint injury on physical examination. The association of MRI\u2010proven joint injury with physical examination\u2013proven joint injury was examined.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 1,110 sites were available to be examined. MRI\u2010proven joint injury was found in 521 sites, whereas the other 589 sites were normal. Physical examination\u2013proven joint injury was found in 305 sites, which was significantly low as compared with MRI\u2010proven joint injury (<jats:italic>P<\/jats:italic> = 1.1 \u00d7 10<jats:sup>\u221212<\/jats:sup> versus MRI). Joint injury on physical examination was not found in 81.5% of the sites where MRI findings were normal. Furthermore, an association of the severity of MRI\u2010proven joint injury with that of joint injury on physical examination was clearly demonstrated (<jats:italic>P<\/jats:italic> = 1.6 \u00d7 10<jats:sup>\u221215<\/jats:sup>, r<jats:sub>s<\/jats:sub> = 0.469).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Our present data suggest that MRI is not only sensitive but accurately reflects the joint injury in patients with early\u2010stage RA.<\/jats:p><\/jats:sec>","DOI":"10.1002\/acr.20395","type":"journal-article","created":{"date-parts":[[2010,11,15]],"date-time":"2010-11-15T11:16:26Z","timestamp":1289819786000},"page":"436-439","source":"Crossref","is-referenced-by-count":27,"title":["Comparative study of the detection of joint injury in early\u2010stage rheumatoid arthritis by magnetic resonance imaging of the wrist and finger joints and physical examination"],"prefix":"10.1002","volume":"63","author":[{"given":"Mami","family":"Tamai","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atsushi","family":"Kawakami","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naoki","family":"Iwamoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shin\u2010Ya","family":"Kawashiri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keita","family":"Fujikawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshiyuki","family":"Aramaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junko","family":"Kita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akitomo","family":"Okada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomohiro","family":"Koga","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuhiko","family":"Arima","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Makoto","family":"Kamachi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoshi","family":"Yamasaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hideki","family":"Nakamura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroaki","family":"Ida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomoki","family":"Origuchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shoichiro","family":"Takao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kiyoshi","family":"Aoyagi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masataka","family":"Uetani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katsumi","family":"Eguchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,2,25]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.berh.2008.09.014"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/ken332"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.198.1.8539375"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780310302"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2005.04138"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2005.043075"},{"key":"e_1_2_6_8_2","first-page":"2154","article-title":"Bone edema determined by magnetic resonance imaging reflects severe disease status in patients with early\u2010stage rheumatoid arthritis","volume":"34","author":"Tamai M","year":"2007","journal-title":"J Rheumatol"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.24711"},{"key":"e_1_2_6_10_2","first-page":"1366","article-title":"OMERACT Rheumatoid Arthritis Magnetic Resonance Imaging Studies. 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