{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T19:43:20Z","timestamp":1789242200117,"version":"build-2803163510"},"reference-count":23,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2011,5,31]],"date-time":"2011-05-31T00:00:00Z","timestamp":1306800000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arthritis Care &amp;amp; Research"],"published-print":{"date-parts":[[2011,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Enthesitis is a major feature of juvenile idiopathic arthritis (JIA) but is difficult to diagnose clinically. Our objective was to compare the accuracy of ultrasonography with power Doppler (US\u2010PD) versus clinical examination for diagnosing enthesitis in patients with JIA and healthy controls.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Twenty\u2010six consecutive patients with JIA and 41 healthy volunteers underwent standardized clinical and US\u2010PD examinations of 5 entheseal sites (proximal and distal quadricepital tendon insertions, Achilles tendon, and plantar fascia). US\u2010PD reproducibility was evaluated. US\u2010PD enthesitis was defined as a PD signal at the enthesis insertion. Bursitis, erosions, and cartilage vascularization were recorded.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In the JIA group, 27 (12.5%) of the entheseal sites exhibited clinical enthesitis (distal patellar ligament in 45% of cases) and 20 (9.4%) exhibited US\u2010PD enthesitis (distal patellar tendon in 30%), including 10 clinically normal sites (50%). US\u2010PD enthesitis was found in several patients with oligoarthritis or polyarthritis. Clinical enthesitis (<jats:italic>P<\/jats:italic> &lt; 0.0001) and HLA\u2013B27\u2013positive (<jats:italic>P<\/jats:italic> = 0.05) status were significantly associated with US\u2010PD enthesitis. Erosion and bursitis, but not tendon thickening, were associated with US\u2010PD enthesitis. US\u2010PD enthesitis was not found at any of the 410 entheseal sites in controls; grade 1 cartilage vascularization was noted at 6% of the control sites.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Enthesitis is a rare phenomenon in JIA. Clinically silent enthesitis is detected by US\u2010PD and can be found in JIA categories other than enthesitis\u2010related arthritis. Tendon thickening and cartilage vascularization can be detected in healthy controls. These findings may have implications for patient classification of the use of US\u2010PD.<\/jats:p><\/jats:sec>","DOI":"10.1002\/acr.20444","type":"journal-article","created":{"date-parts":[[2011,2,10]],"date-time":"2011-02-10T18:08:59Z","timestamp":1297361339000},"page":"849-855","source":"Crossref","is-referenced-by-count":82,"title":["Ultrasonography for detecting enthesitis in juvenile idiopathic arthritis"],"prefix":"10.1002","volume":"63","author":[{"given":"Sandrine","family":"Jousse\u2010Joulin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sylvain","family":"Breton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire","family":"Cangemi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bertrand","family":"Fenoll","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luc","family":"Bressolette","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Loic","family":"de Parscau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alain","family":"Saraux","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Val\u00e9rie","family":"Devauchelle\u2010Pensec","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,5,31]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780291008"},{"key":"e_1_2_6_3_2","first-page":"1520","article-title":"Worldwide prevalence of juvenile arthritis why does it vary so much?","volume":"29","author":"Manners PJ","year":"2002","journal-title":"J Rheumatol"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2007-0291"},{"key":"e_1_2_6_5_2","first-page":"1991","article-title":"Revision of the proposed classification criteria for juvenile idiopathic arthritis: Durban, 1997","volume":"25","author":"Petty RE","year":"1998","journal-title":"J Rheumatol"},{"key":"e_1_2_6_6_2","first-page":"390","article-title":"International League of Associations for Rheumatology classification of juvenile idiopathic arthritis: second revision, Edmonton, 2001","volume":"31","author":"Petty RE","year":"2004","journal-title":"J Rheumatol"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.berh.2005.12.001"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11926-996-0006-6"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780380618"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.22181"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-004-0997-1"},{"key":"e_1_2_6_12_2","first-page":"S50","article-title":"Entheseal involvement","volume":"27","author":"D'Agostino MA","year":"2009","journal-title":"Clin Exp Rheumatol"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1080\/03009740802448833"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1136\/ard.61.10.905"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.10841"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.090354"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.berh.2006.03.007"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.24369"},{"key":"e_1_2_6_19_2","first-page":"848","article-title":"The OMERACT Ultrasound Group: status of current activities and research directions","volume":"34","author":"Wakefield RJ","year":"2007","journal-title":"J Rheumatol"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1186\/ar2665"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.146.1.6849029"},{"key":"e_1_2_6_22_2","doi-asserted-by":"publisher","DOI":"10.1002\/1529-0131(199804)41:4<694::AID-ART17>3.0.CO;2-#"},{"key":"e_1_2_6_23_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.10812"},{"key":"e_1_2_6_24_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.10916"}],"container-title":["Arthritis Care &amp; 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